{"type":"trials","record":{"id":34860,"source_id":"clinicaltrials-gov","external_id":"NCT07049809","title":"Targeting Sarcopenia and Frailty: Multicomponent Exercise With Focal Muscle Vibration","brief_summary":"This study aimed to evaluate the efficacy of multicomponent exercises (aerobic exercises, strength exercises, and balance exercises), individualized with the application of a focal muscle vibration machine at the lower extremities, on parameters of sarcopenia (a muscle disease) in health-related physical fitness, physical performance, frailty levels, and cognitive function, falls, and hospitalizations in older adults. Focal muscle vibration is a type of therapeutic technique used with the application of six capsules placed on the lower extremities, three on each bed, each of which generates a tolerable vibration depending on the stimulation of the muscles. It is neither painful nor counterproductive to the muscles in the lower extremities. Multicomponent exercises refer to the application of exercises through three different modalities: aerobic exercises, strength exercises, and balance exercises. We alternate these three types of exercises to achieve millions of health benefits. The multi-component program will be individualized based on each individual's abilities to avoid risks and achieve maximum benefits.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Universitat Internacional de Catalunya","enrollment":40,"countries":["Spain"],"start_date":"2025-07-02","completion_date":"2025-12-15","last_update_date":"2026-05-04","source_url":"https://clinicaltrials.gov/study/NCT07049809","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"75 Years","comparator":"Multicomponent Exercise Group","organization":"Universitat Internacional de Catalunya","interventions":["Focal Muscle Vibration","Multicomponent Exercise"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Short Physical Performance Battery — From enrollment to the end of treatment at 12 weeks","Demographic and anthropometric assessments — from enrollment to 12 weeks after treatment","Handgrip — from enrollment to 12 weeks after intervention","SARC-F — from enrollment to 12 weeks after intervention.","Clinical Frailty Scale — from enrollment to 12 weeks after intervention","Muscle ultrasound — from enrollment to 12 weeks after intervention.","Mini Mental State Exam — from enrollment to 12 weeks after intervention."],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","source_has_results":false},"controlled_terms":["Sarcopenia","Frailty at Older Adults","Cognitive Impairment","Adherence","Focal Muscle Vibration","Multicomponent Exercise"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct07049809","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-07-02 to 2025-12-15","comparator":"Multicomponent Exercise Group","confidence":"structured-source","population":"ALL · 75 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.784Z","intervention":["Focal Muscle Vibration","Multicomponent Exercise"],"participants":40,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Short Physical Performance Battery — From enrollment to the end of treatment at 12 weeks","Demographic and anthropometric assessments — from enrollment to 12 weeks after treatment","Handgrip — from enrollment to 12 weeks after intervention","SARC-F — from enrollment to 12 weeks after intervention.","Clinical Frailty Scale — from enrollment to 12 weeks after intervention","Muscle ultrasound — from enrollment to 12 weeks after intervention.","Mini Mental State Exam — from enrollment to 12 weeks after intervention."],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"exercise","is_published":true,"match_reasons":["Title contains controlled term: exercise.","Abstract contains controlled term: exercise.","Source terminology contains: exercise.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Exercise","slug":"exercise"}},{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}},{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Abstract contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/34860","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}