{"type":"trials","record":{"id":34895,"source_id":"clinicaltrials-gov","external_id":"NCT07529470","title":"Rockwood Frailty Index and Survival in Hospital-at-Home Patients","brief_summary":"Frailty is a key determinant of prognosis in older adults with complex chronic conditions and in palliative care settings. The Rockwood Frailty Index (RFI), based on the accumulation of health deficits, has demonstrated prognostic value across multiple clinical contexts. This study evaluates the association between the RFI and overall survival in complex chronic and palliative patients (oncologic and non-oncologic) treated in a Hospital-at-Home (HaH) unit.","overall_status":"Completed","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Instituto de Investigacion Sanitaria La Fe","enrollment":2610,"countries":["Spain"],"start_date":"2021-01-01","completion_date":"2024-12-31","last_update_date":"2026-04-21","source_url":"https://clinicaltrials.gov/study/NCT07529470","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":"DOMMOR","age_range":"65 Years","comparator":null,"organization":"Instituto de Investigacion Sanitaria La Fe","interventions":["Patients identified and followed in this cohort received scheduled supportive telephone calls every two weeks if classi…"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Overall Survival — 1 year","Comparative prognostic performance of the Rockwood Frailty Index versus Charlson Comorbidity Index — 1 year","Association between age and overall survival — 1 year","Association between sex and overall survival — 1 year","Association between overall survival and clinical variables (Charlson Comorbidity Index) — 1 year","Association between overall survival and clinical variables (Barthel Index) — 1 year","Association between overall survival and laboratory parameters (C-reactive protein) — 1 year","Association between overall survival and laboratory parameters (albumin) — 1 year"],"design_description":null,"source_has_results":false},"controlled_terms":["Home Care Services, Hospital-Based","Frailty","Mortality","Palliative Care","Patients identified and followed in this cohort received scheduled supportive telephone calls every two weeks if classi…"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: frailty, frailty index.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct07529470","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2021-01-01 to 2024-12-31","comparator":null,"confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.443Z","intervention":["Patients identified and followed in this cohort received scheduled supportive telephone calls every two weeks if classi…"],"participants":2610,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Overall Survival — 1 year","Comparative prognostic performance of the Rockwood Frailty Index versus Charlson Comorbidity Index — 1 year","Association between age and overall survival — 1 year","Association between sex and overall survival — 1 year","Association between overall survival and clinical variables (Charlson Comorbidity Index) — 1 year","Association between overall survival and clinical variables (Barthel Index) — 1 year","Association between overall survival and laboratory parameters (C-reactive protein) — 1 year","Association between overall survival and laboratory parameters (albumin) — 1 year"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty, frailty index.","Abstract contains controlled term: frailty, frailty index.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/34895","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}