{"type":"trials","record":{"id":34900,"source_id":"clinicaltrials-gov","external_id":"NCT07302568","title":"Exercise and Gezaixi Interventions on Community-Dwelling Older Adults","brief_summary":"This interventional study evaluates a 12-week, once-weekly group exercise program combining 60 minutes of progressive strength training and 60 minutes of Taiwanese opera-based activities for community-dwelling adults aged ≥65 in Taipei. The primary aim is to delay frailty and functional decline by improving physical fitness and independence. Primary outcomes are muscle strength, calf circumference, and SOF frailty score; secondary outcomes are BSRS-5, GGDS-5, and SARC-F. The study uses a non-randomized, parallel two-arm design (exercise vs. usual activity), open-label, with assessments at baseline and week 12.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"National Taipei University of Nursing and Health Sciences","enrollment":120,"countries":["Taiwan"],"start_date":"2025-12-20","completion_date":"2026-03-20","last_update_date":"2026-04-17","source_url":"https://clinicaltrials.gov/study/NCT07302568","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years to 90 Years","comparator":"Usual Activity","organization":"National Taipei University of Nursing and Health Sciences","interventions":["Strength Training plus Taiwanese Opera-based Activities"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Muscle Strength — From enrollment to the end of intervention at 12 week","Calf Circumference — rom enrollment to the end of treatment at 12 weeks","Study of Osteoporotic Fractures (SOF) frailty score — From enrollment to the end of treatment at 12 week","Brief Symptom Rating Scale 5-item (BSRS-5) — From enrollment to the end of treatment at 12 weeks","Geriatric Depression Scale score 5-item(GGDS-5) — From enrollment to the end of treatment at 12 weeks","SARC-F — From enrollment to the end of treatment at 12 weeks"],"design_description":"NON RANDOMIZED · PARALLEL · PREVENTION · NONE","source_has_results":false},"controlled_terms":["Frailty","Functional Decline","Community-Dwelling Older Adults","Strength Training plus Taiwanese Opera-based Activities"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: exercise.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct07302568","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-12-20 to 2026-03-20","comparator":"Usual Activity","confidence":"structured-source","population":"ALL · 65 Years to 90 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.787Z","intervention":["Strength Training plus Taiwanese Opera-based Activities"],"participants":120,"study_design":"NON RANDOMIZED · PARALLEL · PREVENTION · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Muscle Strength — From enrollment to the end of intervention at 12 week","Calf Circumference — rom enrollment to the end of treatment at 12 weeks","Study of Osteoporotic Fractures (SOF) frailty score — From enrollment to the end of treatment at 12 week","Brief Symptom Rating Scale 5-item (BSRS-5) — From enrollment to the end of treatment at 12 weeks","Geriatric Depression Scale score 5-item(GGDS-5) — From enrollment to the end of treatment at 12 weeks","SARC-F — From enrollment to the end of treatment at 12 weeks"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"exercise","is_published":true,"match_reasons":["Title contains controlled term: exercise.","Abstract contains controlled term: exercise.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Exercise","slug":"exercise"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/34900","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}