{"type":"trials","record":{"id":34911,"source_id":"clinicaltrials-gov","external_id":"NCT07472530","title":"Respiratory Exercises in Frail Elderly COPD Patients","brief_summary":"Purpose: This study evaluated the impact of a structured intervention on frailty, lung function, physical capacity, and dyspnea in elderly COPD patients. COPD, common in older adults, often coexists with frailty, which worsens health outcomes. While pulmonary rehabilitation improves function, its effect on frailty remains unclear. Procedures: A total of 66 patients with a confirmed diagnosis of COPD were randomly allocated into two equal groups: an intervention group (n=33) and a control group (n=33). Participants in the intervention group completed a six-week pulmonary rehabilitation program. Both baseline and post-intervention evaluations comprised spirometric measurements (FVC, FEV1, FEV1/FVC ratio, FEF25-75, and PEF), the Edmonton Frailty Scale (EFS), the six-minute walk test (6MWT), oxygen saturation levels, and assessments of dyspnea severity. Results: Significant improvements were observed in the intervention group in FVC, FEV1, FEV1/FVC, and PEF (p\\<0.05). Total EFS scores and subdimensions such as mood, general health, and cognitive status also improved significantly (p\\<0.05). Additionally, the intervention group showed increased 6MWT distance, higher oxygen saturation, and reduced dyspnea scores post-intervention (p\\<0.05), with minimal changes in the control group. Conclusion: The findings suggest that pulmonary rehabilitation not only enhances pulmonary function and exercise capacity but also reduces frailty severity in elderly COPD patients. Integrating frailty-focused strategies into routine COPD management may improve outcomes and quality of life in this population.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Çankırı Karatekin University","enrollment":66,"countries":["Turkey (Türkiye)"],"start_date":"2023-08-01","completion_date":"2023-10-30","last_update_date":"2026-04-13","source_url":"https://clinicaltrials.gov/study/NCT07472530","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years","comparator":"Control Group without Breathing Exercises","organization":"Çankırı Karatekin University","interventions":["breathing exercises"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Pulmonary Function Test (PFT)-FVC — 8 WEEKS","Pulmonary Function Test (PFT)- FEV1 — 8 WEEKS","Pulmonary Function Test (PFT)- FEF25-75 — 8 WEEKS"],"design_description":"RANDOMIZED · PARALLEL · OTHER · SINGLE","source_has_results":false},"controlled_terms":["Fraility","COPD (Chronic Obstructive Pulmonary Disease)","Older Adults (65 Years and Older)","breathing exercises"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: exercise.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct07472530","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2023-08-01 to 2023-10-30","comparator":"Control Group without Breathing Exercises","confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.445Z","intervention":["breathing exercises"],"participants":66,"study_design":"RANDOMIZED · PARALLEL · OTHER · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Pulmonary Function Test (PFT)-FVC — 8 WEEKS","Pulmonary Function Test (PFT)- FEV1 — 8 WEEKS","Pulmonary Function Test (PFT)- FEF25-75 — 8 WEEKS"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"exercise","is_published":true,"match_reasons":["Title contains controlled term: exercise.","Abstract contains controlled term: exercise.","Source terminology contains: exercise.","Title supplies longevity context: frail, elderly.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Exercise","slug":"exercise"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/34911","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}