{"type":"trials","record":{"id":34920,"source_id":"clinicaltrials-gov","external_id":"NCT07519603","title":"Frailty in Older Adults With Chronic Obstructive Pulmonary Disease (COPD) and Outcomes of the VIVIFRAIL Program","brief_summary":"Frailty is common among older patients with chronic obstructive pulmonary disease (COPD) and is associated with poor functional outcomes and increased health risks. This study aims to determine the prevalence of frailty and to evaluate the effects of the Vivifrail exercise program on physical performance, activities of daily living, and quality of life in older COPD patients at Hospital 198, Ministry of Public Security, Vietnam.","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"National Geriatric Hospital","enrollment":80,"countries":["Vietnam"],"start_date":"2026-03-01","completion_date":"2027-01-01","last_update_date":"2026-04-09","source_url":"https://clinicaltrials.gov/study/NCT07519603","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":"COPD-FRAIL","age_range":"60 Years","comparator":"Usual Care Group","organization":"National Geriatric Hospital","interventions":["Vivifrail Exercise program","Usual Care Group"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Change in Short Physical Performance Battery (SPPB) score — baseline to 6 months","Change in frailty status assessed by Fried frail — Baseline to 6 months","Change in handgrip strength (kg) — baseline to 6 months","Change in COPD Assessment Test (CAT) score — Baseline to 6 months"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Chronic Obstructive Pulmonary Disease (COPD)","Frailty","Vivifrail Exercise program","Usual Care Group"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct07519603","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2026-03-01 to 2027-01-01","comparator":"Usual Care Group","confidence":"structured-source","population":"ALL · 60 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.446Z","intervention":["Vivifrail Exercise program","Usual Care Group"],"participants":80,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Change in Short Physical Performance Battery (SPPB) score — baseline to 6 months","Change in frailty status assessed by Fried frail — Baseline to 6 months","Change in handgrip strength (kg) — baseline to 6 months","Change in COPD Assessment Test (CAT) score — Baseline to 6 months"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/34920","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}