{"type":"trials","record":{"id":34946,"source_id":"clinicaltrials-gov","external_id":"NCT06280586","title":"Effectiveness of Intervention in Prevention of Sarcopenia, Frailty and Functional Decline in Pre-frail Community Elderly","brief_summary":"Frailty is a geriatric syndrome characterized by a decrease in the function of various organs and systems that leads to a greater risk of suffering from diseases or disabilities. Frailty is usually accompanied by weight loss, loss of strength, slowing of walking speed, fatigue and poor physical activity. Frail people have more difficulty in carrying out the usual activities of daily life and a greater risk of needing help to be able to do them. The aim of this study is to evaluate the safety and effectiveness of an intervention based on the control of chronic diseases, a good use of medicines, diet, physical exercise and good social support, in the prevention . of frailty in old people who are at risk of frailty. These criteria for participating in the study are why we invite you to participate. Your participation is voluntary. Your decision to participate or not in the study will not affect the medical care you may need. Before making a decision, read this information sheet carefully and ask the person who informs you the questions you want. In the study there will be two groups, one will receive the study intervention and the other will not receive any special treatment (we call it the control group). The assignment of each individual to one group or the other will take place once you have decided to participate. This assignment will be made at random so that neither you nor your doctor can know \"a priori\" which group you will be in.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Consorci Sanitari del Maresme","enrollment":232,"countries":["Spain"],"start_date":"2021-11-15","completion_date":"2024-12-31","last_update_date":"2026-03-27","source_url":"https://clinicaltrials.gov/study/NCT06280586","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":"ESPAI-F","age_range":"70 Years","comparator":"Control","organization":"Consorci Sanitari del Maresme","interventions":["Multidisciplinary intervention"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Muscle Mass — baseline, 6 months and 12 months","Muscle strength and/or Muscle function — baseline, 6 months and 12 months","Sarcopenia — baseline, 6 months and 12 months","Frailty — baseline, 6 months and 12 months","Functional Capacity 1 — baseline, 6 months and 12 months","Functional Capacity 2 — baseline, 6 months and 12 months","Functional Capacity 3 — baseline, 6 months and 12 months","Functional Capacity 4 — baseline, 6 months and 12 months","Functional Capacity 5 — baseline, 6 months and 12 months","Functional Capacity 6 — baseline, 6 months and 12 months"],"design_description":"RANDOMIZED · PARALLEL · PREVENTION · SINGLE","source_has_results":false},"controlled_terms":["Muscle Strengh","Frailty","Sarcopenia","Multidisciplinary intervention"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct06280586","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2021-11-15 to 2024-12-31","comparator":"Control","confidence":"structured-source","population":"ALL · 70 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.793Z","intervention":["Multidisciplinary intervention"],"participants":232,"study_design":"RANDOMIZED · PARALLEL · PREVENTION · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Muscle Mass — baseline, 6 months and 12 months","Muscle strength and/or Muscle function — baseline, 6 months and 12 months","Sarcopenia — baseline, 6 months and 12 months","Frailty — baseline, 6 months and 12 months","Functional Capacity 1 — baseline, 6 months and 12 months","Functional Capacity 2 — baseline, 6 months and 12 months","Functional Capacity 3 — baseline, 6 months and 12 months","Functional Capacity 4 — baseline, 6 months and 12 months","Functional Capacity 5 — baseline, 6 months and 12 months","Functional Capacity 6 — baseline, 6 months and 12 months"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}},{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/34946","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}