{"type":"trials","record":{"id":34956,"source_id":"clinicaltrials-gov","external_id":"NCT06975449","title":"Effectiveness of Graded Training in the Vivifrail Exercise Program Among Long-Term Care Residents","brief_summary":"This study evaluates the effectiveness of the Vivifrail multicomponent physical exercise program among elderly residents with different levels of frailty in long-term care centers. A 12-week intervention will be conducted in randomly assigned experimental and control groups. Outcomes include physical performance, fall risk, grip strength, calf circumference, and ICOPE function.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"China Medical University Hospital","enrollment":80,"countries":["Taiwan"],"start_date":"2025-05-20","completion_date":"2026-02-20","last_update_date":"2026-03-24","source_url":"https://clinicaltrials.gov/study/NCT06975449","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"70 Years","comparator":"Control Group: Usual Care","organization":"China Medical University Hospital","interventions":["Multicomponent Physical Exercise Program (Vivifrail)"],"registry_source":"ClinicalTrials.gov","outcome_measures":["SPPB Score change at Weeks 0, 4, 8, 12, 16, 20, 24 — SPPB Score change at Weeks 0, 4, 8, 12, 16, 20, 24","Fall risk assessment (TUG, gait speed, number of falls) at Weeks 0, 4, 8, 12, 16, 20, 24 — Fall risk assessment (TUG, g…","ICOPE function assessment at Weeks 0, 12, 24 — ICOPE function assessment at Weeks 0, 12, 24","Grip strength (hand dynamometer) at Weeks 0, 12, 24 — Grip strength (hand dynamometer) at Weeks 0, 12, 24"],"design_description":"RANDOMIZED · SEQUENTIAL · PREVENTION · NONE","source_has_results":false},"controlled_terms":["Frailty","Physical Inactivity","Aging","Multicomponent Physical Exercise Program (Vivifrail)"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: exercise.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct06975449","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-05-20 to 2026-02-20","comparator":"Control Group: Usual Care","confidence":"structured-source","population":"ALL · 70 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.452Z","intervention":["Multicomponent Physical Exercise Program (Vivifrail)"],"participants":80,"study_design":"RANDOMIZED · SEQUENTIAL · PREVENTION · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["SPPB Score change at Weeks 0, 4, 8, 12, 16, 20, 24 — SPPB Score change at Weeks 0, 4, 8, 12, 16, 20, 24","Fall risk assessment (TUG, gait speed, number of falls) at Weeks 0, 4, 8, 12, 16, 20, 24 — Fall risk assessment (TUG, g…","ICOPE function assessment at Weeks 0, 12, 24 — ICOPE function assessment at Weeks 0, 12, 24","Grip strength (hand dynamometer) at Weeks 0, 12, 24 — Grip strength (hand dynamometer) at Weeks 0, 12, 24"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"exercise","is_published":true,"match_reasons":["Title contains controlled term: exercise.","Abstract contains controlled term: exercise.","Source terminology contains: exercise.","Title supplies longevity context: frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Exercise","slug":"exercise"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/34956","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}