{"type":"trials","record":{"id":34961,"source_id":"clinicaltrials-gov","external_id":"NCT07486661","title":"A Pilot Project for PLWH Aged 65-75: Preventing the Development of Frailty","brief_summary":"In ageing populations, the main risk is the development of a syndrome of frailty, characterized by the addition of polymorbidity, polymedication, psychosocial difficulties, cognitive disorders, ... This functional decline is linked to a reduction in the person's functional reserves, and will lead to an increase in health problems, hospitalizations and, ultimately, mortality. People living with HIV (PLWH) over 50 develop the same kind of comorbidities as HIV-uninfected people over 75 years-old. In Belgium, the care of PLWH\\< 75 years with frailty syndrome is not reimbursed by healthcare insurance, and geriatric assessment and management is therefore not possible in this age group, despite the very real need. Goals of this project are: 1. Determine the proportion and characterize the population of PLWH aged 65 and over who screen positive using the Fried scale 2. Validate the application of the Fried scale in a population of PLWH 3. Offer a care pathway model to prevent the onset of frailty in people screened as at-risk and who do not benefit from routine screening or care pathway reimbursement. Projets proposal: * Systematic screening of all PLWH aged 65-74 at the MIA Center, by the nurse prior to physician consultation, using the Fried scale. * Send all PLWH aged 65-74 who screen positive to Geriatric One Day for an ergo-geriatric consultation to confirm the risk of frailty and set up a preventive care pathway * After treatment, perform a patient satisfaction questionnaire + a new Fried scale at one year","overall_status":"Recruiting","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Centre Hospitalier Universitaire Saint Pierre","enrollment":100,"countries":["Belgium"],"start_date":"2025-08-28","completion_date":"2028-07-01","last_update_date":"2026-03-20","source_url":"https://clinicaltrials.gov/study/NCT07486661","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":"Frailty","age_range":"65 Years to 74 Years","comparator":null,"organization":"Centre Hospitalier Universitaire Saint Pierre","interventions":[],"registry_source":"ClinicalTrials.gov","outcome_measures":["number of PLWH between 65 and 74 years with frailty — Baseline","Number of PLWH with a Fried test detecting frailty — Baseline","Number of PLWH with Fried scale detecting pre-frailty condition — Baseline","Results of Fried scale at one year — one year after the first Fried scale performed at baseline"],"design_description":null,"source_has_results":false},"controlled_terms":["Age Group: 65-74","HIV"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct07486661","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-08-28 to 2028-07-01","comparator":null,"confidence":"structured-source","population":"ALL · 65 Years to 74 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.453Z","intervention":[],"participants":100,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["number of PLWH between 65 and 74 years with frailty — Baseline","Number of PLWH with a Fried test detecting frailty — Baseline","Number of PLWH with Fried scale detecting pre-frailty condition — Baseline","Results of Fried scale at one year — one year after the first Fried scale performed at baseline"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/34961","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}