{"type":"trials","record":{"id":34990,"source_id":"clinicaltrials-gov","external_id":"NCT07443722","title":"The Beneficial Effects of Nutritional Supplements on the Malnutrition and Sarcopenia Risk in Elderly Living Alone","brief_summary":"This study aims to examine the effects of meal delivery services on the nutritional status and mobility of malnourished older adults living alone at a foundation in Taoyuan. Participants will continue their usual diet and consume a daily oral nutrition supplement (ONS) of their preferred type (instant powder with milk or soy milk), provided monthly by social workers for 12 months. Nutritional assessments will be conducted every three months, including the Mini Nutritional Assessment (MNA), anthropometric measures, and 24-hour dietary recall. Mobility will be evaluated using grip strength, walking speed, chair stand test, and calf circumference. Psychological outcomes will be assessed every six months using a quality-of-life questionnaire and the short form of the Geriatric Depression Scale. This study is expected to determine whether regular meal delivery services can improve nutritional status, mobility, quality of life, and depressive symptoms among elderly individuals living alone.","overall_status":"Active Not Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Taipei Medical University","enrollment":30,"countries":["Taiwan"],"start_date":"2025-09-01","completion_date":"2026-08-31","last_update_date":"2026-03-02","source_url":"https://clinicaltrials.gov/study/NCT07443722","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Active Not Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years","comparator":null,"organization":"Taipei Medical University","interventions":["milk drinks"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Change in Mini Nutritional Assessment (MNA) score — Baseline, 3 months, 6 months, 9 months and 12 months","Change in body weight — Baseline, 3 months, 6 months, 9 months and 12 months","Change in body mass index (BMI) — Baseline, 3 months, 6 months, 9 months, 12 months","Change in skeletal muscle mass — Baseline, 3 months, 6 months, 9 months, 12 months","Changes in calf circumference — Baseline, 3 months, 6 months, 9 months and 12 months","Changes in muscle strength — Baseline, 3 months, 6 months, 9 months and 12 months","Change in five-times chair stand test time — Baseline, 3 months, 6 months, 9 months and 12 months","Change in gait speed — Baseline, 3 months, 6 months, 9 months and 12 months","Changes in daily total energy intake — Baseline, 3 months, 6 months, 9 months and 12 months","Change in daily protein intake — Baseline, 3months, 6 months, 9 months, 12 months","Change in daily carbohydrate intake — Baseline, 3 months, 6 months, 9 months, 12 months","Change in daily fat intake — Baseline, 3 months, 6 months, 9 months, 12 months","Change in Short-Form Geriatric Depression Scale (GDS-5) score — Baseline, 6 months and 12 months","Change in World Health Organization Quality of Life-BREF (WHOQOL-BREF) score — Baseline, 6 months and 12 months"],"design_description":"NA · SINGLE GROUP · SUPPORTIVE CARE · NONE","source_has_results":false},"controlled_terms":["Valid Malnutrition Condition","Valid Sarcopenia","Valid Frailty","milk drinks"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct07443722","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-09-01 to 2026-08-31","comparator":null,"confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.797Z","intervention":["milk drinks"],"participants":30,"study_design":"NA · SINGLE GROUP · SUPPORTIVE CARE · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Change in Mini Nutritional Assessment (MNA) score — Baseline, 3 months, 6 months, 9 months and 12 months","Change in body weight — Baseline, 3 months, 6 months, 9 months and 12 months","Change in body mass index (BMI) — Baseline, 3 months, 6 months, 9 months, 12 months","Change in skeletal muscle mass — Baseline, 3 months, 6 months, 9 months, 12 months","Changes in calf circumference — Baseline, 3 months, 6 months, 9 months and 12 months","Changes in muscle strength — Baseline, 3 months, 6 months, 9 months and 12 months","Change in five-times chair stand test time — Baseline, 3 months, 6 months, 9 months and 12 months","Change in gait speed — Baseline, 3 months, 6 months, 9 months and 12 months","Changes in daily total energy intake — Baseline, 3 months, 6 months, 9 months and 12 months","Change in daily protein intake — Baseline, 3months, 6 months, 9 months, 12 months","Change in daily carbohydrate intake — Baseline, 3 months, 6 months, 9 months, 12 months","Change in daily fat intake — Baseline, 3 months, 6 months, 9 months, 12 months","Change in Short-Form Geriatric Depression Scale (GDS-5) score — Baseline, 6 months and 12 months","Change in World Health Organization Quality of Life-BREF (WHOQOL-BREF) score — Baseline, 6 months and 12 months"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: elderly.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/34990","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}