{"type":"trials","record":{"id":35012,"source_id":"clinicaltrials-gov","external_id":"NCT07418762","title":"Community-Based Program Integrating Nurse-Led Mind-Body Exercise and Nutrition for Frailty","brief_summary":"This study aims to develop and evaluate a community-based rehabilitation program integrating nurse-led mind-body exercises and nutritional supplementation for frail older adults in Indonesia. This study uses a Randomized Controlled Trial (RCT) with three parallel groups and assessor blinding. The intervention was conducted for 8 weeks in community-dwelling older adults aged ≥ 65 years who live within the working area of a Community Health Center in Surabaya City. The sample size is 48 elderly. Participants will be divided into 3 groups: the control group, the Nurse-Led Mind-Body Exercise group, and the MBE + Nutritional Supplementation (MBE + Nutrition) group. The procedure is carried out after respondents provide voluntary consent. Confidentiality and anonymity of data will be strictly maintained throughout the research process. Data analysis between groups and within groups will be conducted using repeated-measures ANOVA and Intention-to-treat (ITT) analysis.","overall_status":"Not Yet Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Universitas Airlangga","enrollment":48,"countries":["Indonesia"],"start_date":"2026-03-30","completion_date":"2026-05-25","last_update_date":"2026-02-18","source_url":"https://clinicaltrials.gov/study/NCT07418762","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":"N-CARE Frailty","age_range":"65 Years to 75 Years","comparator":"Control","organization":"Universitas Airlangga","interventions":["Nurse-Led Mind-Body Exercise (MBE)"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Changes in frailty status of the elderly — Baseline (Week 0) and post-intervention at Week 8","Changes in Lower Extremity Physical Performance of the Elderly — Baseline (Week 0) and post-intervention at Week 8","Changes in Functional Mobility and Fall Risk of the Elderly — Baseline (Week 0) and post-intervention at Week 8","Changes in Pulmonary Function of the Elderly — Baseline (Week 0) and post-intervention at Week 8","Changes in Body Composition of the Elderly — Baseline (Week 0) and post-intervention at Week 8","Changes in Inflammatory Biomarkers Related to Frailty of the Elderly — Baseline (Week 0) and post-intervention at Week 8"],"design_description":"RANDOMIZED · PARALLEL · HEALTH SERVICES RESEARCH · DOUBLE","source_has_results":false},"controlled_terms":["Frail Elderly","Nurse-Led Mind-Body Exercise (MBE)"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: exercise.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct07418762","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2026-03-30 to 2026-05-25","comparator":"Control","confidence":"structured-source","population":"ALL · 65 Years to 75 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.461Z","intervention":["Nurse-Led Mind-Body Exercise (MBE)"],"participants":48,"study_design":"RANDOMIZED · PARALLEL · HEALTH SERVICES RESEARCH · DOUBLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Changes in frailty status of the elderly — Baseline (Week 0) and post-intervention at Week 8","Changes in Lower Extremity Physical Performance of the Elderly — Baseline (Week 0) and post-intervention at Week 8","Changes in Functional Mobility and Fall Risk of the Elderly — Baseline (Week 0) and post-intervention at Week 8","Changes in Pulmonary Function of the Elderly — Baseline (Week 0) and post-intervention at Week 8","Changes in Body Composition of the Elderly — Baseline (Week 0) and post-intervention at Week 8","Changes in Inflammatory Biomarkers Related to Frailty of the Elderly — Baseline (Week 0) and post-intervention at Week 8"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"exercise","is_published":true,"match_reasons":["Title contains controlled term: exercise.","Abstract contains controlled term: exercise.","Source terminology contains: exercise.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Exercise","slug":"exercise"}},{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","title context","study type"],"relevance_score":80,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35012","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}