{"type":"trials","record":{"id":35050,"source_id":"clinicaltrials-gov","external_id":"NCT07367828","title":"Validity of Frailty Screening Tools as a Measure for Postoperative Outcomes","brief_summary":"Frailty is a common geriatric syndrome defined as a clinical state of decreased physiologic reserve resulting in increased vulnerability to stressors. It is associated with several unfavorable postoperative complications independent of age such as readmission, length of hospital stay and mortality. To address these concerns, medical societies have acknowledged a need for routine screening to identify elderly patients who are at high risk for major complications before undergoing surgery. In the absence of a golden standard for frailty assessment, there are multiple assessment tools available. However, the challenge with many frailty tools is that they can be time-consuming, and require expertise and clinical training.This poses a challenge for screening a large elderly population before surgery. Some frailty assessment tools, such as PRISMA7 (The Program of Research to Integrate Services for the Maintenance of Autonomy), timed up and go (TUG) and the clock drawing test (CDT), have been demonstrated to be quick, simple and easy to use with minimal training. The PRISMA-7 is a frailty screening questionnaire that consists of seven dichotomous items considering age, gender, health problems that affect activities of daily living (ADLs), assistance from others with ADLs, having to count on someone if needed, and the use of mobility aids. The TUG test is used for assessing fall risk and frailty in older patients. It is measured by the time it takes an individual to stand up from a seated position, walk three meters and return back to a seated position. There is no standard cut-off for TUG, however, a cut-off of \\> 10 seconds has been used to identify frailty. Cognitive impairment in older surgical patients may predispose patients to executive dysfunction that many elderly patients experience postoperatively and has shown to be a risk factor for surgical complications. Some studies suggest a strong relationship between cognitive impairment and physical frailty resulting in cognitive frailty when evaluating older adults.The CDT has shown to be a valuable screening tool for cognitive concerns. When administering the CDT, a patient receives instructions to draw a clock. Performing the test requires auditory comprehension, planning, sustained attention, visual-spatial skills and executive skills. The prevalence of surgical frailty in Iceland has not been researched thoroughly enough to provide an accurate estimate. This is important to reveal the number of senior surgical patients at high risk of adverse postoperative outcomes who could benefit from a preoperative intervention. However, there is a lack of consensus on an optimal frailty assessment to screen patients for identifying frail patients prior to surgery, and more research is needed to evaluate which group of patients would benefit the most from prehabilitation. The scientific value of this study is to elucidate the extent of frailty risk and its associated postoperative outcomes in older surgical…","overall_status":"Recruiting","phases":[],"study_type":"OBSERVATIONAL","sponsor":"University of Iceland","enrollment":350,"countries":["Iceland"],"start_date":"2025-01-20","completion_date":"2026-12-21","last_update_date":"2026-01-26","source_url":"https://clinicaltrials.gov/study/NCT07367828","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"70 Years","comparator":null,"organization":"University of Iceland","interventions":["Intermediate/major elective surgery"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Moderate and severe surgical complications (Clavien-Dindo ≥2) — Time frame: From the same day after surgery to postoper…","90-day Readmission — From the day of surgery to postoperative day 90.","Length of hospital stay — From the day of primary surgery until discharge from the index hospitalization (same-day disc…","Postoperative delirium during primary hospitalization — From the day of surgery (postoperative day 0) until first docum…","Short-term mortality — Up to 1 year after the primary surgery","Non-home discharge — From the day of surgery (postoperative day 0) until discharge to a non-home destination or dischar…"],"design_description":null,"source_has_results":false},"controlled_terms":["Frailty in Adult Surgery","Frailty Syndrome","Elective Surgery","Intermediate/major elective surgery"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct07367828","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-01-20 to 2026-12-21","comparator":null,"confidence":"structured-source","population":"ALL · 70 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.467Z","intervention":["Intermediate/major elective surgery"],"participants":350,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Moderate and severe surgical complications (Clavien-Dindo ≥2) — Time frame: From the same day after surgery to postoper…","90-day Readmission — From the day of surgery to postoperative day 90.","Length of hospital stay — From the day of primary surgery until discharge from the index hospitalization (same-day disc…","Postoperative delirium during primary hospitalization — From the day of surgery (postoperative day 0) until first docum…","Short-term mortality — Up to 1 year after the primary surgery","Non-home discharge — From the day of surgery (postoperative day 0) until discharge to a non-home destination or dischar…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35050","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}