{"type":"trials","record":{"id":35052,"source_id":"clinicaltrials-gov","external_id":"NCT06089083","title":"PROmOting Gynecologic Cancer Patients With Frailty to Achieve Functional Recovery","brief_summary":"This study seeks to understand how frailty, a term that describes people who are more vulnerable stressors such as a new medical problem, affects the outcomes and quality of life in adult patients with gynecologic cancer.","overall_status":"Recruiting","phases":[],"study_type":"OBSERVATIONAL","sponsor":"University of California, San Francisco","enrollment":500,"countries":["United States"],"start_date":"2023-10-18","completion_date":"2033-11-30","last_update_date":"2026-01-26","source_url":"https://clinicaltrials.gov/study/NCT06089083","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"FEMALE","acronym":"PROOF","age_range":"18 Years","comparator":null,"organization":"University of California, San Francisco","interventions":["Physical function assessment","Self-reported Assessments and Questionnaires","Surgery (Standard of Care, Non-Interventional)"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Proportion of participants who are categorized as frail — At time of enrollment, 1 day","Demographic risk factors associated with those who screen positive for frailty — At time of enrollment, 1 day","Oncologic risk factors associated with those who screen positive for frailty — At time of enrollment, 1 day","Mean number of healthy days at home — Up to 10 years","Mean length of hospital stay — Up to 10 years","Percentage of participants readmitted to hospital — Up to 10 years","Percentage of participants with reported surgical complications — Up to 10 years","Mean time to initiation of standard of care chemotherapy — Up to 10 years","Median Progression Free Survival (PFS) — Up to 10 years","Median Overall Survival (OS) — Up to 10 years","Mean number of treatment delays — Up to 10 years"],"design_description":null,"source_has_results":false},"controlled_terms":["Malignant Female Reproductive System Neoplasm","Gynecologic Cancer","Gynecologic Neoplasm","Physical function assessment","Self-reported Assessments and Questionnaires","Surgery (Standard of Care, Non-Interventional)"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct06089083","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2023-10-18 to 2033-11-30","comparator":null,"confidence":"structured-source","population":"FEMALE · 18 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.467Z","intervention":["Physical function assessment","Self-reported Assessments and Questionnaires","Surgery (Standard of Care, Non-Interventional)"],"participants":500,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Proportion of participants who are categorized as frail — At time of enrollment, 1 day","Demographic risk factors associated with those who screen positive for frailty — At time of enrollment, 1 day","Oncologic risk factors associated with those who screen positive for frailty — At time of enrollment, 1 day","Mean number of healthy days at home — Up to 10 years","Mean length of hospital stay — Up to 10 years","Percentage of participants readmitted to hospital — Up to 10 years","Percentage of participants with reported surgical complications — Up to 10 years","Mean time to initiation of standard of care chemotherapy — Up to 10 years","Median Progression Free Survival (PFS) — Up to 10 years","Median Overall Survival (OS) — Up to 10 years","Mean number of treatment delays — Up to 10 years"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35052","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}