{"type":"trials","record":{"id":35079,"source_id":"clinicaltrials-gov","external_id":"NCT07322861","title":"Virtual Reality-Based vs Traditional Physiotherapy for Balance, Frailty, and Fall Prevention in Adults Aged 45 Years and Older","brief_summary":"This study will compare two exercise-based rehabilitation programs to improve balance and reduce fall risk in adults aged 45 years and older who have had at least one fall in the past year or have balance problems. Participants will be assigned to one of two groups: (1) a virtual reality (VR) exercise program using the PABLO system, or (2) a traditional physiotherapy program based on the Otago approach. Both programs will include balance training, strength/power exercises, aerobic activity, and flexibility. The program will last 12 weeks, with two supervised sessions per week (about 30 minutes each). Assessments will be completed at the start of the study and again after 12 weeks. The main outcomes include frailty status, number of falls, mobility (Timed Up and Go test), and balance (Berg Balance Scale). Additional outcomes include grip strength, quality of life (SF-12), and program adherence and safety. The study will help determine whether VR-based rehabilitation improves participation and outcomes compared with traditional physiotherapy.","overall_status":"Not Yet Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Umm Al-Qura University","enrollment":80,"countries":[],"start_date":"2026-01-01","completion_date":"2026-06-01","last_update_date":"2026-01-07","source_url":"https://clinicaltrials.gov/study/NCT07322861","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:25:30.723+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"40 Years","comparator":"Traditional Physiotherapy Program","organization":"Umm Al-Qura University","interventions":["Virtual Reality-Based Training Program","Physiotherapy Exercise Program"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Frailty Status (Arabic FRAIL Scale) — Baseline (Week 0) and Post-Intervention (Week 12)","Balance Performance (Berg Balance Scale) — Baseline (Week 0) and Post-Intervention (Week 12)","Functional Mobility (Timed Up and Go Test) — Time Frame: Baseline (Week 0) and Post-Intervention (Week 12)","Number of Falls — Baseline (previous 12 months) and During Intervention (Weeks 1-12)","Grip Strength — Baseline (previous 12 months) and During Intervention (Weeks 1-12)","Quality of Life (SF-12) — Baseline (previous 12 months) and During Intervention (Weeks 1-12)"],"design_description":"NON RANDOMIZED · PARALLEL · PREVENTION · SINGLE","source_has_results":false},"controlled_terms":["Frailty","Falls","Balance Deficits","Mobility Limitations","Virtual Reality-Based Training Program","Physiotherapy Exercise Program"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:25:35.871646+00:00","duplicate_cluster_key":"id:nct07322861","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2026-01-01 to 2026-06-01","comparator":"Traditional Physiotherapy Program","confidence":"structured-source","population":"ALL · 40 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:25:30.737Z","intervention":["Virtual Reality-Based Training Program","Physiotherapy Exercise Program"],"participants":80,"study_design":"NON RANDOMIZED · PARALLEL · PREVENTION · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Frailty Status (Arabic FRAIL Scale) — Baseline (Week 0) and Post-Intervention (Week 12)","Balance Performance (Berg Balance Scale) — Baseline (Week 0) and Post-Intervention (Week 12)","Functional Mobility (Timed Up and Go Test) — Time Frame: Baseline (Week 0) and Post-Intervention (Week 12)","Number of Falls — Baseline (previous 12 months) and During Intervention (Weeks 1-12)","Grip Strength — Baseline (previous 12 months) and During Intervention (Weeks 1-12)","Quality of Life (SF-12) — Baseline (previous 12 months) and During Intervention (Weeks 1-12)"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35079","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}