{"type":"trials","record":{"id":35110,"source_id":"clinicaltrials-gov","external_id":"NCT07073703","title":"Effectiveness of a Personalized 6-month Programme on Frailty in Older Patients Treated for Bladder or Kidney Cancer.","brief_summary":"Bladder and kidney cancers are commonly diagnosed in older adults. Surgery remains the primary treatment modality for patients with kidney or bladder cancer. In older patients, common co-morbidities include fatigue, physical deconditioning characterized by reduced cardiorespiratory fitness and progressing sarcopenia, pain- whether disease- related or treatment-induced- and undernutrition. These factors increased the risk of post-operative complications and exacerbate patient frailty. The investigators propose a personalized 6-month program both pre- and post-surgery, including adapted physical activity sessions, therapeutic education workshops, and systematic referral to the department's DAPAP program.","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Centre Hospitalier Universitaire de Saint Etienne","enrollment":106,"countries":["France"],"start_date":"2025-12-03","completion_date":"2028-03-01","last_update_date":"2025-12-09","source_url":"https://clinicaltrials.gov/study/NCT07073703","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T07:05:20.248+00:00","metadata":{"sex":"ALL","acronym":"FRAGECO","age_range":"65 Years","comparator":"Control group","organization":"Centre Hospitalier Universitaire de Saint Etienne","interventions":["APA","Therapeutic education workshops","DAPAP"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Patient frailty — Day : 1 and Month : 6","Cumulative Illness Rating Scale for Geriatrics (CIRS-G) — Months : 1, 2, 3 and 6","Fried's frailty phenotype (FP) — Months : 1, 2, 3 and 6","level of physical activity — Months : 1, 2, 3 and 6","level of sedentary lifestyle — Months : 1, 2, 3 and 6","Nutritional status — Months : 1, 2, 3 and 6","Memory — Months : 1, 2, 3 and 6","Healthy quality of life — Months : 1, 2, 3 and 6","Fatigue — Months : 1, 2, 3 and 6","Depression — Months : 1, 2, 3 and 6","Muscular strength — Months : 1, 2, 3 and 6","Balance — Months : 1, 2, 3 and 6"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Bladder (Urothelial, Transitional Cell) Cancer","Kidney (Renal Cell) Cancer","APA","Therapeutic education workshops","DAPAP"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T07:05:30.295959+00:00","duplicate_cluster_key":"id:nct07073703","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-12-03 to 2028-03-01","comparator":"Control group","confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T07:05:20.291Z","intervention":["APA","Therapeutic education workshops","DAPAP"],"participants":106,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Patient frailty — Day : 1 and Month : 6","Cumulative Illness Rating Scale for Geriatrics (CIRS-G) — Months : 1, 2, 3 and 6","Fried's frailty phenotype (FP) — Months : 1, 2, 3 and 6","level of physical activity — Months : 1, 2, 3 and 6","level of sedentary lifestyle — Months : 1, 2, 3 and 6","Nutritional status — Months : 1, 2, 3 and 6","Memory — Months : 1, 2, 3 and 6","Healthy quality of life — Months : 1, 2, 3 and 6","Fatigue — Months : 1, 2, 3 and 6","Depression — Months : 1, 2, 3 and 6","Muscular strength — Months : 1, 2, 3 and 6","Balance — Months : 1, 2, 3 and 6"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35110","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}