{"type":"trials","record":{"id":35136,"source_id":"clinicaltrials-gov","external_id":"NCT06891573","title":"South Korean Study to Prevent Frailty and Aging-related Diseases Through Lifestyle Intervention","brief_summary":"The goal of this feasibility randomized controlled trial is to investigate the applicability of software that aims to improve symptoms of frailty by implementing customized interventions such as physical exercise and cognitive training implemented through a mobile app for 16 weeks for patients diagnosed with frailty or prefrailty. The primary outcomes are adherence, retention rates, and recruitment rates. Participants will participate in customized interventions including physical exercise, cognitive training, nutritional guidance, and management of disease related to frailty for 16 weeks.","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Seong Hye Choi, MD","enrollment":40,"countries":["South Korea"],"start_date":"2025-02-26","completion_date":"2026-01-15","last_update_date":"2025-11-20","source_url":"https://clinicaltrials.gov/study/NCT06891573","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":"SUPERAGING","age_range":"60 Years to 90 Years","comparator":"Control","organization":"Inha University Hospital","interventions":["Lifestyle Management"],"registry_source":"ClinicalTrials.gov","outcome_measures":["retention rate — From enrollment to the end of intervention at 16 weeks","Adherence to the protocol — From enrollment to the end of intervention at 16 weeks","recruitment rate — From enrollment to the end of intervention at 16 weeks","Change from Baseline in Korean Frailty Index for Primary Care at 16 weeks — From baseline to the end of intervention at…","Change from Baseline in Modified Fried frailty phenotype score at 16 weeks — From baseline to the end of intervention a…","Change from Baseline in Lubben Social Network Scale at 16 weeks — From baseline to the end of intervention at 16 weeks","Change from Baseline in 14-item cognitive subscale of the Alzheimer's Disease Assessment Scale at 16 weeks — From basel…","Change from Baseline in Korean Mini-Mental State Examination-2 at 16 weeks — From enrollment to the end of intervention…","Change from Baseline in Clinical Dementia Rating scale-Sum of Boxes at 16 weeks — From baseline to the end of intervent…","Change from Baseline in Korean Instrumental Activities of Daily Living at 16 weeks — From baseline to the end of interv…","Change from Baseline in Modified Barthel Index: at 16 weeks — From baseline to the end of intervention at 16 weeks","Change from Baseline in Center for Epidemiological Studies-Depression Scale at 16 weeks — From baseline to the end of i…","Change from Baseline in Quality of life-Alzheimer's disease at 16 weeks — From baseline to the end of intervention at 1…","Change from Baseline in gait speed at 16 weeks — From baseline to the end of intervention at 16 weeks","Change from Baseline in Short Physical Performance Battery at 16 weeks — From baseline to the end of intervention at 16…","Change from Baseline inTimed Up and Go test at 16 weeks — From baseline to the end of intervention at 16 weeks","Change from Baseline in 30 s sit-to-stand at 16 weeks — From baseline to the end of intervention at 16 weeks","Change from Baseline in 2 min stepping test at 16 weeks — From baseline to the end of intervention at 16 weeks","Change from Baseline in Mini Nutritional Assessment at 16 weeks — From baseline to the end of intervention at 16 weeks","Change from Baseline in Nutritional Quotient for Elderly at 16 weeks — From baseline to the end of intervention at 16 w…"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","source_has_results":false},"controlled_terms":["Frailty","Lifestyle Management"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct06891573","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-02-26 to 2026-01-15","comparator":"Control","confidence":"structured-source","population":"ALL · 60 Years to 90 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.480Z","intervention":["Lifestyle Management"],"participants":40,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["retention rate — From enrollment to the end of intervention at 16 weeks","Adherence to the protocol — From enrollment to the end of intervention at 16 weeks","recruitment rate — From enrollment to the end of intervention at 16 weeks","Change from Baseline in Korean Frailty Index for Primary Care at 16 weeks — From baseline to the end of intervention at…","Change from Baseline in Modified Fried frailty phenotype score at 16 weeks — From baseline to the end of intervention a…","Change from Baseline in Lubben Social Network Scale at 16 weeks — From baseline to the end of intervention at 16 weeks","Change from Baseline in 14-item cognitive subscale of the Alzheimer's Disease Assessment Scale at 16 weeks — From basel…","Change from Baseline in Korean Mini-Mental State Examination-2 at 16 weeks — From enrollment to the end of intervention…","Change from Baseline in Clinical Dementia Rating scale-Sum of Boxes at 16 weeks — From baseline to the end of intervent…","Change from Baseline in Korean Instrumental Activities of Daily Living at 16 weeks — From baseline to the end of interv…","Change from Baseline in Modified Barthel Index: at 16 weeks — From baseline to the end of intervention at 16 weeks","Change from Baseline in Center for Epidemiological Studies-Depression Scale at 16 weeks — From baseline to the end of i…","Change from Baseline in Quality of life-Alzheimer's disease at 16 weeks — From baseline to the end of intervention at 1…","Change from Baseline in gait speed at 16 weeks — From baseline to the end of intervention at 16 weeks","Change from Baseline in Short Physical Performance Battery at 16 weeks — From baseline to the end of intervention at 16…","Change from Baseline inTimed Up and Go test at 16 weeks — From baseline to the end of intervention at 16 weeks","Change from Baseline in 30 s sit-to-stand at 16 weeks — From baseline to the end of intervention at 16 weeks","Change from Baseline in 2 min stepping test at 16 weeks — From baseline to the end of intervention at 16 weeks","Change from Baseline in Mini Nutritional Assessment at 16 weeks — From baseline to the end of intervention at 16 weeks","Change from Baseline in Nutritional Quotient for Elderly at 16 weeks — From baseline to the end of intervention at 16 w…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: aging, frailty.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35136","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}