{"type":"trials","record":{"id":35200,"source_id":"clinicaltrials-gov","external_id":"NCT06812286","title":"TrackFrailty Project","brief_summary":"The TRACKFRAILTY project aims to answer the following main research questions: i) What is the prevalence of physical frailty in individuals living in residential care facilities (RCF) from Portugal's Cova da Beira subregion (Interior Center Region)? ii) What factors best predict frailty status? iii) Is strength training effective in reversing physical frailty in RCF residents? iv) In the long term, what dose of strength training volume is needed to promote the most significant health benefits in frail RCF residents? Based on these research questions, the TRACKFRAILTY project aims to quantify the prevalence of frailty in Portuguese RCF residents from the Cova da Beira subregion and analyze the effects of long-term strength training with different volumes on reversing physical frailty.","overall_status":"Active Not Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"University of Beira Interior","enrollment":45,"countries":["Portugal"],"start_date":"2025-06-01","completion_date":"2026-07-01","last_update_date":"2025-08-29","source_url":"https://clinicaltrials.gov/study/NCT06812286","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Active Not Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":"TrackFrailty","age_range":"50 Years","comparator":null,"organization":"University of Beira Interior","interventions":["Less-volume","More-volume","Control"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Frailty phenotype — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","Short Physical Performance Battery (SPPB) — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","10-meter walking test — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","6-minute walking test — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","Handgrip strength — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","1-kg medicine ball throw — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","Montreal Cognitive Assessment (MoCA) — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","Satisfaction With Life Scale (SWLS) — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","Geriatric Depression Scale (GDS) — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","Geriatric Anxiety Inventory (GAI) — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","Brief 2-Way Social Support Scale (SSS) — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","6-item De Jong Gierveld Loneliness Scale (DJGLS-6) — Baseline and after 10, 20, and 30 weeks of intervention (4 time po…","Health-Related Quality of Life 36-Item Short Form Survey (SF-36) — Baseline and after 10, 20, and 30 weeks of intervent…","Falls — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","Recruitment, Retention, and Adherence Rates (Feasibility) — Baseline and after 10, 20, and 30 weeks of intervention (4…","Incidence of Adverse Events during Intervention (Safety) — Baseline and after 10, 20, and 30 weeks of intervention (4 t…"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","source_has_results":false},"controlled_terms":["Frailty Syndrome","Less-volume","More-volume","Control"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct06812286","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-06-01 to 2026-07-01","comparator":null,"confidence":"structured-source","population":"ALL · 50 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.489Z","intervention":["Less-volume","More-volume","Control"],"participants":45,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Frailty phenotype — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","Short Physical Performance Battery (SPPB) — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","10-meter walking test — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","6-minute walking test — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","Handgrip strength — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","1-kg medicine ball throw — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","Montreal Cognitive Assessment (MoCA) — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","Satisfaction With Life Scale (SWLS) — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","Geriatric Depression Scale (GDS) — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","Geriatric Anxiety Inventory (GAI) — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","Brief 2-Way Social Support Scale (SSS) — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","6-item De Jong Gierveld Loneliness Scale (DJGLS-6) — Baseline and after 10, 20, and 30 weeks of intervention (4 time po…","Health-Related Quality of Life 36-Item Short Form Survey (SF-36) — Baseline and after 10, 20, and 30 weeks of intervent…","Falls — Baseline and after 10, 20, and 30 weeks of intervention (4 time points).","Recruitment, Retention, and Adherence Rates (Feasibility) — Baseline and after 10, 20, and 30 weeks of intervention (4…","Incidence of Adverse Events during Intervention (Safety) — Baseline and after 10, 20, and 30 weeks of intervention (4 t…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35200","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}