{"type":"trials","record":{"id":35215,"source_id":"clinicaltrials-gov","external_id":"NCT07100366","title":"Comparing Sarcopenia , Physical, Psychological and Social Frailty in Hospitalized Older Women Congestive Heart Failure in Metropolitan and Rural Settings","brief_summary":"Frailty-encompassing sarcopenia, physical, psychological, and social frailty-is common among older adults with congestive heart failure (CHF) and contributes to adverse outcomes such as rehospitalization, mortality, and poor quality of life. However, few studies have compared these conditions in congestive heart failure (CHF) patients, particularly in elderly women in Taiwan, and effective, tailored Information and Communication Technology (ICT) interventions are scarce. This three-year study aims to (1) compare baseline characteristics and incidence rates of sarcopenia, physical, psychological, and social frailty among hospitalized older women with congestive heart failure (CHF) in metropolitan versus rural hospitals; (2) evaluate risk factors associated with physical, psychological, and social frailty; (3) monitor health outcomes (rehospitalization, mortality, quality of life) during a one-year follow-up; and (4) assess the effectiveness of an Information and Communication Technology (ICT) intervention designed to enhance social connectivity and emotional well-being. In Phase 1, clinical data-including ejection fraction, congestive heart failure (CHF) stage, and comorbidity -will be collected using the 2024 Guidelines of the Taiwan Society of Cardiology, while sarcopenia will be identified via Asian Working Group for Sarcopenia (AWGS) guidelines. Physical, psychological, and social frail will be measured with the Tilburg Frailty Indicator (TFI) and Makizako's Social Frailty Questionnaire, respectively, and physical activity will be assessed using the IPAQ-S. Phase 2 will involve quarterly follow-ups over one year to compare health outcomes between metropolitan and rural settings, and to develop a predictive model of these outcomes. Phase 3 employs a quasi-experimental design with 90 participants randomized into three groups: an Information and Communication Technology (ICT) intervention group (using a dedicated app for at least 15 minutes daily, which monitors emotional status), a community-based social participation group, and a control group maintaining routine care. Key outcomes (mood, physical activity, frailty measures, and clinical status) will be assessed at baseline, immediately post-intervention, and three months thereafter. This study is expected to identify significant differences between settings and demonstrate that a tailored Information and Communication Technology (ICT) intervention can improve social connectivity and clinical outcomes in older women with congestive heart failure (CHF).","overall_status":"Not Yet Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Chang Gung University of Science and Technology","enrollment":200,"countries":[],"start_date":"2025-09-01","completion_date":"2028-07-31","last_update_date":"2025-08-15","source_url":"https://clinicaltrials.gov/study/NCT07100366","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years","comparator":"control group","organization":"Chang Gung University of Science and Technology","interventions":["ChatGPT","community social"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Tilburg Frailty Indicator (TFI) — Baseline, 3-month follow-up","Makizako Social Frailty Index — Baseline, 3-month follow-up","International Physical Activity Questionnaire - Short Form (IPAQ-S) — Baseline, 3-month follow-up","Minnesota Living with Heart Failure Questionnaire（MLHFQ） — Baseline, 3-month follow-up","UCLA Loneliness Scale — Baseline, 3-month follow-up","Geriatric Depression Scale (GDS-15) — Baseline, 3-month follow-up","Clinical Frailty Scale (CFS) — Baseline, 3-month follow-up"],"design_description":"RANDOMIZED · PARALLEL · HEALTH SERVICES RESEARCH · NONE","source_has_results":false},"controlled_terms":["65 Years Older","CHF - Congestive Heart Failure","Social Communication","Sarcopenia in Elderly","ChatGPT","community social"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct07100366","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-09-01 to 2028-07-31","comparator":"control group","confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.816Z","intervention":["ChatGPT","community social"],"participants":200,"study_design":"RANDOMIZED · PARALLEL · HEALTH SERVICES RESEARCH · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Tilburg Frailty Indicator (TFI) — Baseline, 3-month follow-up","Makizako Social Frailty Index — Baseline, 3-month follow-up","International Physical Activity Questionnaire - Short Form (IPAQ-S) — Baseline, 3-month follow-up","Minnesota Living with Heart Failure Questionnaire（MLHFQ） — Baseline, 3-month follow-up","UCLA Loneliness Scale — Baseline, 3-month follow-up","Geriatric Depression Scale (GDS-15) — Baseline, 3-month follow-up","Clinical Frailty Scale (CFS) — Baseline, 3-month follow-up"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}},{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Abstract contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35215","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}