{"type":"trials","record":{"id":35262,"source_id":"clinicaltrials-gov","external_id":"NCT05935319","title":"VIVIFRAIL Program in Improving the Frailty and Physical Function in the Elderly","brief_summary":"The global population is aging, and Taiwan has become an aging society. The aging population continues to rise. When the physical function and mental state of the elderly gradually decline, it is easy for the elderly to enter a state of physical weakness. Weakness is the decline in the reserve capacity of the physiological system. It is also related to geriatric syndrome, causing falls, hospitalization, disability, death, and increased medical costs, burden on primary caregivers, and reduced quality of life for the elderly. Physical exercise training has been considered to be an effective strategy to prevent and delay disability and frailty, so this study uses the Vivifrail program for the elderly. A family-based 12-week exercise program, including: resistance, strength, balance, flexibility and cardiorespiratory endurance exercise training, performed five days a week, at least 45-60 minutes each time, so that the elderly can exercise at home, It can also improve physical function and improve the quality of life. This study adopts a randomized controlled trial (RCT) with a one-group pretest-posttest design, with pre-frail and frail elderly as the research objects, and uses comprehensive assessment of the elderly to understand the physical function of the elderly Status, Vivifrail for the elderly was provided for abnormal physical function items, and post-test evaluation was carried out 4 weeks and 12 weeks after the intervention. In Taiwan, there is no research on Vivifrail for the frail elderly. In view of this, it is hoped that through the Vivifrail program and the follow-up of case managers, multi-faceted and continuous integrated care can be provided. Improve and maintain the physical function of the frail elderly for reference in the daily care of the elderly in the future.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"National Taipei University of Nursing and Health Sciences","enrollment":200,"countries":["Taiwan"],"start_date":"2023-05-26","completion_date":"2025-03-31","last_update_date":"2025-07-11","source_url":"https://clinicaltrials.gov/study/NCT05935319","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years","comparator":"control group","organization":"National Taipei University of Nursing and Health Sciences","interventions":["Vivifrail"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Hand Grip — 1-2 minutes","Short Physical Performance Battery(SPPB) — 5-10 minutes","Activities of Daily Living(ADL) — 2-5 minutes","Instrumental Activities of Daily Living(IADL) — 2-5 minutes","Mini-Mental State Examination(MMSE) — 10-20 minutes","Geriatric Depression Scale(GDS- 15) — 10-20 minutes"],"design_description":"RANDOMIZED · PARALLEL · HEALTH SERVICES RESEARCH · SINGLE","source_has_results":false},"controlled_terms":["Frailty","Physical Activity","Cognitive Function","Vivifrail"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct05935319","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2023-05-26 to 2025-03-31","comparator":"control group","confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.499Z","intervention":["Vivifrail"],"participants":200,"study_design":"RANDOMIZED · PARALLEL · HEALTH SERVICES RESEARCH · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Hand Grip — 1-2 minutes","Short Physical Performance Battery(SPPB) — 5-10 minutes","Activities of Daily Living(ADL) — 2-5 minutes","Instrumental Activities of Daily Living(IADL) — 2-5 minutes","Mini-Mental State Examination(MMSE) — 10-20 minutes","Geriatric Depression Scale(GDS- 15) — 10-20 minutes"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35262","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}