{"type":"trials","record":{"id":35268,"source_id":"clinicaltrials-gov","external_id":"NCT06882720","title":"Effects of Otago-based Multicomponent Exercise on Sarcopenia in Pre-Frailty Older Adults in Nursing Homes: A Randomized Controlled Trial","brief_summary":"The objective of this clinical trial is to understand the efficacy of a targeted exercise program (Otago exercise program+Strength training) in elderly people with prefrailty and sarcopenia. The trial aims to answer the following main questions: * Is OEP+ST effective in elderly people with prefrailty and sarcopenia? * In what areas did participants improve during the OEP+ST intervention? Researchers will randomly assign participants to an experimental group (OEP+ST) and a control group (daily care only) for comparison to see the effects of this intervention. Participants in the EG group will: * Exercise 3 times a week for 1 hour each time (including 10 minutes of warm-up, 40 minutes of exercise and 10 minutes of stretching) At the same time, it is necessary to walk for 30-40 minutes three times a week. It lasts for three months. * Test and record their condition (including frailty, body composition, physical function, quality of life) before and after the experiment.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Gdansk University of Physical Education and Sport","enrollment":61,"countries":["China"],"start_date":"2025-03-27","completion_date":"2025-06-28","last_update_date":"2025-07-03","source_url":"https://clinicaltrials.gov/study/NCT06882720","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":"PA&P-F&SP","age_range":"65 Years to 89 Years","comparator":"Control group","organization":"Gdansk University of Physical Education and Sport","interventions":["Exercise"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Gait Speed — From enrollment to the end of treatment at 2 weeks","Skeletal muscle index — From enrollment to the end of treatment at 2 weeks","Hand Strength — From enrollment to the end of treatment at 2 weeks","Skeletal Muscle Mass — From enrollment to the end of treatment at 2 weeks","Body Fat Mass — From enrollment to the end of treatment at 2 weeks","Skeletal Lean Mass — From enrollment to the end of treatment at 2 weeks","Fat-Free Mass — From enrollment to the end of treatment at 2 weeks","TUG — From enrollment to the end of treatment at 2 weeks","ArmCurl — From enrollment to the end of treatment at 2 weeks","6MWT — From enrollment to the end of treatment at 2 weeks","5 STS — From enrollment to the end of treatment at 2 weeks","TandemBalance — From enrollment to the end of treatment at 2 weeks"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · TRIPLE","source_has_results":false},"controlled_terms":["Pre-Frailty","Sarcopenia in Elderly","Exercise"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct06882720","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-03-27 to 2025-06-28","comparator":"Control group","confidence":"structured-source","population":"ALL · 65 Years to 89 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.820Z","intervention":["Exercise"],"participants":61,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · TRIPLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Gait Speed — From enrollment to the end of treatment at 2 weeks","Skeletal muscle index — From enrollment to the end of treatment at 2 weeks","Hand Strength — From enrollment to the end of treatment at 2 weeks","Skeletal Muscle Mass — From enrollment to the end of treatment at 2 weeks","Body Fat Mass — From enrollment to the end of treatment at 2 weeks","Skeletal Lean Mass — From enrollment to the end of treatment at 2 weeks","Fat-Free Mass — From enrollment to the end of treatment at 2 weeks","TUG — From enrollment to the end of treatment at 2 weeks","ArmCurl — From enrollment to the end of treatment at 2 weeks","6MWT — From enrollment to the end of treatment at 2 weeks","5 STS — From enrollment to the end of treatment at 2 weeks","TandemBalance — From enrollment to the end of treatment at 2 weeks"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}},{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Abstract contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35268","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}