{"type":"trials","record":{"id":35270,"source_id":"clinicaltrials-gov","external_id":"NCT05047237","title":"Electronic Frailty Index (eFI)Cacious-Diabetes Care","brief_summary":"The purpose of this research is to explore whether a pharmacist-led diabetes management program can help optimize diabetes care for older adults. Participation in this study will involve meeting with a pharmacist who works with subjects' doctors, getting some routine bloodwork typical for people with diabetes, and potentially adjusting the subject's diabetes medications to reach American Diabetes Association guidelines. This study aims to bring older adults with diabetes whose measurements and medications are different from the guidelines of the American Diabetes Association into guidelines-based ranges.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Wake Forest University Health Sciences","enrollment":42,"countries":["United States"],"start_date":"2021-10-29","completion_date":"2025-05-31","last_update_date":"2025-07-02","source_url":"https://clinicaltrials.gov/study/NCT05047237","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years","comparator":"Control; Active Decliners","organization":"Wake Forest University Health Sciences","interventions":["Pharmacist-Led Optimization Intervention"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Proportion of subjects who Achieve Glycosylated Hemoglobin (HbA1c) values — Month 6","Change in HbA1c — From Baseline through Month 6","Random Glucose Measurements — From Baseline through Month 12","Estimated Change in Out-of-Pocket Costs — From Baseline through Month 6","Point estimates of Feasibility Measures: Participation/Reach — Month 6","Point estimates of Feasibility Measures: Number Contacted/Reach — Month 6","Point estimates of Feasibility Measures: Number at Risk/Reach — Month 6","Feasibility Measures: Effort Required to Enroll-Number Calls — Month 6","Feasibility Measures: Effort Required to Enroll-Average Call Duration — Month 6","Point estimates of Feasibility Measure-Number of Visits — Month 12","Point estimates of Feasibility Measures: Time — Month 12","Rate of Emergency Department Visits and Hospitalizations — Baseline through Month 18","Number of Hypoglycemic Events Requiring Medical Assistance — Time Frame: Baseline through Month 18","Number of Injurious Falls — Baseline through Month 18","Mortality — Baseline through Month 18","Implementation Metric--Feasibility — Baseline through Month 18","Implementation Metric-- Acceptability — Baseline through Month 18","Implementation Metric-- Appropriateness — Baseline through Month 18","Implementation Metric- Value — Baseline through Month 18"],"design_description":"NON RANDOMIZED · PARALLEL · SUPPORTIVE CARE · NONE","source_has_results":false},"controlled_terms":["Diabetes","Type2 Diabetes","Pharmacist-Led Optimization Intervention"],"relevance_confidence":80,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: frailty, frailty index.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct05047237","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2021-10-29 to 2025-05-31","comparator":"Control; Active Decliners","confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.501Z","intervention":["Pharmacist-Led Optimization Intervention"],"participants":42,"study_design":"NON RANDOMIZED · PARALLEL · SUPPORTIVE CARE · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Proportion of subjects who Achieve Glycosylated Hemoglobin (HbA1c) values — Month 6","Change in HbA1c — From Baseline through Month 6","Random Glucose Measurements — From Baseline through Month 12","Estimated Change in Out-of-Pocket Costs — From Baseline through Month 6","Point estimates of Feasibility Measures: Participation/Reach — Month 6","Point estimates of Feasibility Measures: Number Contacted/Reach — Month 6","Point estimates of Feasibility Measures: Number at Risk/Reach — Month 6","Feasibility Measures: Effort Required to Enroll-Number Calls — Month 6","Feasibility Measures: Effort Required to Enroll-Average Call Duration — Month 6","Point estimates of Feasibility Measure-Number of Visits — Month 12","Point estimates of Feasibility Measures: Time — Month 12","Rate of Emergency Department Visits and Hospitalizations — Baseline through Month 18","Number of Hypoglycemic Events Requiring Medical Assistance — Time Frame: Baseline through Month 18","Number of Injurious Falls — Baseline through Month 18","Mortality — Baseline through Month 18","Implementation Metric--Feasibility — Baseline through Month 18","Implementation Metric-- Acceptability — Baseline through Month 18","Implementation Metric-- Appropriateness — Baseline through Month 18","Implementation Metric- Value — Baseline through Month 18"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty, frailty index.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","title context","study type"],"relevance_score":80,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35270","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}