{"type":"trials","record":{"id":35330,"source_id":"clinicaltrials-gov","external_id":"NCT05384730","title":"Frail2Fit Study: Online Nutrition and Exercise Support for Older Adults With Frailty","brief_summary":"Frail2Fit will explore the feasibility of training volunteers to deliver online nutrition, exercise, and behaviour change (supported self-management) to improve the health of older people after discharge from hospital. The study also aims to explore if the supported self-management is acceptable to older people, their family members and/or carers, and the volunteers. Between 30-60% of older people in hospital lose muscle strength and function (deconditioning) and around 14% of older adults in hospital are frail. Reduced muscle function and frailty increase risk of poor health outcomes, including reduced quality of life, increased risk of hospital readmission and increased risk of mortality. Therefore, intervening to prevent functional decline is a high-priority patient-centred outcome. Current evidence suggest that physical activity (PA) and nutrition interventions are key to maintaining independence and improving frailty status. In response to the COVID-19 restrictions, healthcare and rehabilitation have increasingly turned to virtual modes of delivery, such as telehealth methods. The increasing use of technology in the daily lives of many allows PA and nutrition interventions to be delivered online. For instance, the investigators have developed and evaluated a programme using online clinics to successfully support over 600 cancer patients living at home to stay active and eat well with provision of emotional support (SafeFit study). With many older people now using the internet for social connection, the team have an opportunity to investigate whether a similar model can improve the health of older people. This study aims to explore the feasibility and acceptability of implementing volunteer-led online exercise and nutrition support to frail older people discharged from hospital. The investigators aim to develop and evaluate a training programme for volunteers, determine the acceptability of the intervention through qualitative methods and identify facilitators and barriers to its implementation. The investigators will also explore the impact of the intervention on health outcomes for older people to inform future trial.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"University Hospital Southampton NHS Foundation Trust","enrollment":32,"countries":["United Kingdom"],"start_date":"2022-10-28","completion_date":"2024-01-10","last_update_date":"2025-05-23","source_url":"https://clinicaltrials.gov/study/NCT05384730","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years","comparator":null,"organization":"University Hospital Southampton NHS Foundation Trust","interventions":["Group nutrition and exercise support"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Volunteers Trained — 6 months","Volunteer Retention — 6 months","Adherence - Online — post-intervention = 3-months","Adherence - Telephone Support — post-intervention= 3-months","Device-based Physical Activity Levels — Baseline, post-intervention (3-months) and follow-up (6-months)","Functional Ability — Baseline, post-intervention (3-months) and follow-up (6-months)","Appetite — Baseline, Post-intervention (3-month) and follow-up (6-month)","Well-being — Baseline, Post-intervention (3-month) and follow-up (6-month)","Depression and Anxiety — Baseline, post-intervention (3-month) and follow-up (6-month)","Patient's Subjective Assessment of Quality of Life — Baseline, Post-intervention (3-month) and follow-up (6-month)","Self-efficacy for Managing Chronic Disease — Baseline, Post-intervention (3-month) and follow-up (6-month)","Self-reported Physical Activity — Baseline, Post-Intervention (3-month), Follow-Up (6-months)"],"design_description":"NA · SINGLE GROUP · OTHER · NONE","source_has_results":true},"controlled_terms":["Frailty","Malnutrition","Sedentary Behavior","Group nutrition and exercise support"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct05384730","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2022-10-28 to 2024-01-10","comparator":null,"confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.509Z","intervention":["Group nutrition and exercise support"],"participants":32,"study_design":"NA · SINGLE GROUP · OTHER · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Volunteers Trained — 6 months","Volunteer Retention — 6 months","Adherence - Online — post-intervention = 3-months","Adherence - Telephone Support — post-intervention= 3-months","Device-based Physical Activity Levels — Baseline, post-intervention (3-months) and follow-up (6-months)","Functional Ability — Baseline, post-intervention (3-months) and follow-up (6-months)","Appetite — Baseline, Post-intervention (3-month) and follow-up (6-month)","Well-being — Baseline, Post-intervention (3-month) and follow-up (6-month)","Depression and Anxiety — Baseline, post-intervention (3-month) and follow-up (6-month)","Patient's Subjective Assessment of Quality of Life — Baseline, Post-intervention (3-month) and follow-up (6-month)","Self-efficacy for Managing Chronic Disease — Baseline, Post-intervention (3-month) and follow-up (6-month)","Self-reported Physical Activity — Baseline, Post-Intervention (3-month), Follow-Up (6-months)"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35330","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}