{"type":"trials","record":{"id":35370,"source_id":"clinicaltrials-gov","external_id":"NCT05738252","title":"Frailty Assessments for Risk Assessment in Gynecologic Oncology Patients","brief_summary":"FARGO is a prospective cohort study that aims to determine the performance of preoperative frailty assessment based on the Frailty Phenotype (FP), compared to a perioperative cardiovascular risk assessment based on the combination of preoperative Revised Cardiac Risk Index (RCRI), age and occurrence of myocardial injury after noncardiac surgery (MINS), in predicting the composite of all-cause death or new disability at 6 months after surgery in patients aged 55 or older. Patients will have confirmed or suspected gynecologic cancer, undergoing cytoreductive or high-risk surgery with or without chemotherapy.","overall_status":"Recruiting","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Population Health Research Institute","enrollment":280,"countries":["Canada"],"start_date":"2023-06-15","completion_date":"2025-10-01","last_update_date":"2025-04-16","source_url":"https://clinicaltrials.gov/study/NCT05738252","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"FEMALE","acronym":"FARGO","age_range":"55 Years to 110 Years","comparator":null,"organization":"Population Health Research Institute","interventions":["Clinical Frailty Scale","Frailty Phenotype"],"registry_source":"ClinicalTrials.gov","outcome_measures":["All-cause death or new disability at 6 months — 6 months","All cause death — 28 days and 1 year","Oncologic Outcomes: Progression Free Survival (PFS) — at 6 and 12 months","Oncologic Outcomes: Cancer-specific death — at 6 and 12 months","New Disability — 28 days, 6 months and 1 year after surgery","Major vascular complications — at 28 days, 6 months, and 1 year after surgery","Infection, and infection with sepsis — at 28 days, 6 months, and 1 year after surgery","In-hospital delirium — During the index hospital admission for surgery up to the first 3 days after surgery or before d…","Bleeding Independently Associated with Mortality after noncardiac Surgery — 28 days after surgery","Acute congestive heart failure — 28 days after surgery, 6 months and 1 year after surgery","Unplanned admission to ICU — during index hospitalization for surgery","New clinically important atrial fibrillation — 28 days after surgery, 6 months and 1 year after surgery","Length of stay — during index hospitalization for surgery","Chemotherapy-related outcomes: total dose received — Before Surgery, 6-months post-surgery","Chemotherapy-related outcomes: time to completion of all chemotherapy cycles — Before Surgery, 6-months post-surgery","Chemotherapy-related outcomes: patient's decisional regret — Before Surgery, 6-months post-surgery","Chemotherapy-related outcomes: Change in health-related function or well-being — Before Surgery, 6-months post-surgery","Chemotherapy-related outcomes — Before Surgery, 6-months post-surgery"],"design_description":null,"source_has_results":false},"controlled_terms":["Gynecologic Cancer","Frailty","Oncology","Clinical Frailty Scale","Frailty Phenotype"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct05738252","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2023-06-15 to 2025-10-01","comparator":null,"confidence":"structured-source","population":"FEMALE · 55 Years to 110 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.515Z","intervention":["Clinical Frailty Scale","Frailty Phenotype"],"participants":280,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["All-cause death or new disability at 6 months — 6 months","All cause death — 28 days and 1 year","Oncologic Outcomes: Progression Free Survival (PFS) — at 6 and 12 months","Oncologic Outcomes: Cancer-specific death — at 6 and 12 months","New Disability — 28 days, 6 months and 1 year after surgery","Major vascular complications — at 28 days, 6 months, and 1 year after surgery","Infection, and infection with sepsis — at 28 days, 6 months, and 1 year after surgery","In-hospital delirium — During the index hospital admission for surgery up to the first 3 days after surgery or before d…","Bleeding Independently Associated with Mortality after noncardiac Surgery — 28 days after surgery","Acute congestive heart failure — 28 days after surgery, 6 months and 1 year after surgery","Unplanned admission to ICU — during index hospitalization for surgery","New clinically important atrial fibrillation — 28 days after surgery, 6 months and 1 year after surgery","Length of stay — during index hospitalization for surgery","Chemotherapy-related outcomes: total dose received — Before Surgery, 6-months post-surgery","Chemotherapy-related outcomes: time to completion of all chemotherapy cycles — Before Surgery, 6-months post-surgery","Chemotherapy-related outcomes: patient's decisional regret — Before Surgery, 6-months post-surgery","Chemotherapy-related outcomes: Change in health-related function or well-being — Before Surgery, 6-months post-surgery","Chemotherapy-related outcomes — Before Surgery, 6-months post-surgery"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35370","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}