{"type":"trials","record":{"id":35428,"source_id":"clinicaltrials-gov","external_id":"NCT05754021","title":"A Practical Platform for In-Home Remote Monitoring of Cognitive Frailty","brief_summary":"Cognitive frailty, characterized by the coexistence of physical frailty and cognitive impairment, is a robust indicator of cognitive decline. Recognizing its significance, the International Association of Gerontology and Geriatrics and the International Academy on Nutrition and Aging have advocated for the use of cognitive frailty assessment as a means of monitoring the progression of mild cognitive impairment towards debilitating conditions like dementia, Alzheimer's disease, and loss of independence. Despite the clear need, a practical and remotely accessible tool for measuring cognitive frailty is currently lacking, especially within the context of telehealth visits. With telehealth video-conferencing becoming increasingly popular, accepted by healthcare payers, and preferred by older adults who may face difficulties traveling to a clinic, there is a pressing need for a software-based solution for remote cognitive frailty assessment that can be easily integrated into existing telehealth systems. This study proposes designing and validating a video-based solution to remotely monitor cognitive-frailty in older adults.","overall_status":"Completed","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Baylor College of Medicine","enrollment":100,"countries":["United States"],"start_date":"2022-02-01","completion_date":"2025-01-31","last_update_date":"2025-02-14","source_url":"https://clinicaltrials.gov/study/NCT05754021","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"50 Years to 95 Years","comparator":null,"organization":"Baylor College of Medicine","interventions":[],"registry_source":"ClinicalTrials.gov","outcome_measures":["Change in cognitive function from baseline to 6 months and 12 months — baseline, every 2 months, up to 12 months","Change in cognitive frailty performance every other month from baseline to 12 months — baseline, every 2 months, up to…","Change in Physical activity from baseline to 6 months and 12 months — baseline, 6 month, 12 month","Change in Gait speed from baseline to 6 months and 12 months — baseline, 6 month, 12 month","Change in Balance from baseline to 6 months and 12 months — baseline, 6 month, 12 month","Change in physical frailty from baseline to 6 months and 12 months — baseline, 6 months, 12 months"],"design_description":null,"source_has_results":false},"controlled_terms":["Frailty","Cognitive Impairment","Dementia","Cognitive Impairment, Mild","Alzheimer Disease","Alzheimer Disease, Early Onset"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct05754021","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2022-02-01 to 2025-01-31","comparator":null,"confidence":"structured-source","population":"ALL · 50 Years to 95 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.523Z","intervention":[],"participants":100,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Change in cognitive function from baseline to 6 months and 12 months — baseline, every 2 months, up to 12 months","Change in cognitive frailty performance every other month from baseline to 12 months — baseline, every 2 months, up to…","Change in Physical activity from baseline to 6 months and 12 months — baseline, 6 month, 12 month","Change in Gait speed from baseline to 6 months and 12 months — baseline, 6 month, 12 month","Change in Balance from baseline to 6 months and 12 months — baseline, 6 month, 12 month","Change in physical frailty from baseline to 6 months and 12 months — baseline, 6 months, 12 months"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35428","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}