{"type":"trials","record":{"id":35475,"source_id":"clinicaltrials-gov","external_id":"NCT06741878","title":"A Biopsychosocial Approach to Improving Multidimensional Frailty Status in Community-Dwelling Older Adults","brief_summary":"Frailty is a common clinical syndrome that is becoming increasingly important as populations age worldwide. Individuals who are frail are at a higher risk for negative outcomes, such as falls, disability, hospitalizations, and even death. The understanding of frailty has evolved from a straightforward concept to a complex model that includes physical, psychological, cognitive, and social factors. Since frailty is not static and can change over time, early interventions can be beneficial. Nevertheless, research in this area has been challenging due to a lack of agreement on what frailty encompasses and an inadequate understanding of how its different components interact. Defining frailty as a multidimensional issue is essential to recognize the adverse effects that can arise from medical, psychological, and social influences. However, recent studies have not sufficiently addressed how these different aspects work together or developed effective multidimensional interventions.","overall_status":"Not Yet Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Hong Kong Baptist University","enrollment":308,"countries":[],"start_date":"2025-01-01","completion_date":"2026-06-30","last_update_date":"2024-12-19","source_url":"https://clinicaltrials.gov/study/NCT06741878","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"60 Years to 80 Years","comparator":"Exercise Training (Biological) + Board Games (Psychosocial) + Diet Consultation (Nutritional); Exercise Training (Biological) + Diet Consultation (Nutritional); Board Games (Psychosocial) + Diet Consultation (Nutritional); Inactive Control (No Treatment)","organization":"Hong Kong Baptist University","interventions":["Exercise","Psychosocial","Nutritional"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Frailty Status (pre-test) — Pre-test (1st test): before intervention","Frailty Status (2nd test) — 2nd test: after 3-month intervention","Frailty Status (3rd test) — 3rd test: after 6-month follow up","Physical Functioning-- Anthropometic Data (pre-test) — Pre-test (1st test): before intervention","Physical Functioning-- Anthropometric Data (2nd test) — 2nd test: after 3-month intervention","Physical Functioning-- Anthropometric Data (3rd test) — 3rd test: after 6-month follow up","Physical Functioning-- Health Related Information (pre-test) — Pre-test (1st test): before intervention","Physical Functioning-- Health Related Information (2nd test) — 2nd test: after 3-month intervention","Physical Functioning-- Health Related Information (3rd test) — 3rd test: after 6-month follow up","Physical Functioning-- Senior Physical Fitness Test Battery (pre-test) — Pre-test (1st test): before intervention","Physical Functioning-- Senior Physical Fitness Test Battery (2nd test) — 2nd test: after 3-month intervention","Physical Functioning-- Senior Physical Fitness Test Battery (3rd test) — 3rd test: after 6-month follow up","Psychological Functioning (pre-test) — Pre-test (1st test): before intervention","Psychological Functioning (2nd test) — 2nd test: after 3-month intervention","Psychological Functioning (3rd test) — 3rd test: after 6-month follow up","Social Function (pre-test) — Pre-test (1st test): before intervention","Social Function (2nd test) — 2nd test: after 3-month intervention","Social Function (3rd test) — 3rd test: after 6-month follow up","Physical Activity Behavioural Changes (pre-test) — Pre-test (1st test): before intervention","Physical Activity Behavioural Changes (2nd test) — 2nd test: after 3-month intervention"],"design_description":"RANDOMIZED · FACTORIAL · PREVENTION · DOUBLE","source_has_results":false},"controlled_terms":["Frailty in Older Adults","Exercise","Psychosocial","Nutritional"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct06741878","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-01-01 to 2026-06-30","comparator":"Exercise Training (Biological) + Board Games (Psychosocial) + Diet Consultation (Nutritional); Exercise Training (Biological) + Diet Consultation (Nutritional); Board Games (Psychosocial) + Diet Consultation (Nutritional); Inactive Control (No Treatment)","confidence":"structured-source","population":"ALL · 60 Years to 80 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.531Z","intervention":["Exercise","Psychosocial","Nutritional"],"participants":308,"study_design":"RANDOMIZED · FACTORIAL · PREVENTION · DOUBLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Frailty Status (pre-test) — Pre-test (1st test): before intervention","Frailty Status (2nd test) — 2nd test: after 3-month intervention","Frailty Status (3rd test) — 3rd test: after 6-month follow up","Physical Functioning-- Anthropometic Data (pre-test) — Pre-test (1st test): before intervention","Physical Functioning-- Anthropometric Data (2nd test) — 2nd test: after 3-month intervention","Physical Functioning-- Anthropometric Data (3rd test) — 3rd test: after 6-month follow up","Physical Functioning-- Health Related Information (pre-test) — Pre-test (1st test): before intervention","Physical Functioning-- Health Related Information (2nd test) — 2nd test: after 3-month intervention","Physical Functioning-- Health Related Information (3rd test) — 3rd test: after 6-month follow up","Physical Functioning-- Senior Physical Fitness Test Battery (pre-test) — Pre-test (1st test): before intervention","Physical Functioning-- Senior Physical Fitness Test Battery (2nd test) — 2nd test: after 3-month intervention","Physical Functioning-- Senior Physical Fitness Test Battery (3rd test) — 3rd test: after 6-month follow up","Psychological Functioning (pre-test) — Pre-test (1st test): before intervention","Psychological Functioning (2nd test) — 2nd test: after 3-month intervention","Psychological Functioning (3rd test) — 3rd test: after 6-month follow up","Social Function (pre-test) — Pre-test (1st test): before intervention","Social Function (2nd test) — 2nd test: after 3-month intervention","Social Function (3rd test) — 3rd test: after 6-month follow up","Physical Activity Behavioural Changes (pre-test) — Pre-test (1st test): before intervention","Physical Activity Behavioural Changes (2nd test) — 2nd test: after 3-month intervention"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35475","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}