{"type":"trials","record":{"id":35503,"source_id":"clinicaltrials-gov","external_id":"NCT03413449","title":"A Prospective Study Frailty for Esophagectomy and Lung Resection in Thoracic Surgery","brief_summary":"The purpose of this study is to develop an all-encompassing frailty model using laboratory and functional studies. A frailty model will help us determine prior to surgery who will require rehabilitation and skilled nursing needs beyond discharge. This model will also help us determine who will likely be readmitted and why they will be readmitted. Understanding these things can help us prevent some of them from occurring in the future.","overall_status":"Completed","phases":[],"study_type":"OBSERVATIONAL","sponsor":"The Cleveland Clinic","enrollment":360,"countries":["United States"],"start_date":"2018-01-08","completion_date":"2024-11-08","last_update_date":"2024-11-14","source_url":"https://clinicaltrials.gov/study/NCT03413449","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"18 Years","comparator":null,"organization":"The Cleveland Clinic","interventions":["Frailty model"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Morbidity — Assessed at discharge and will be reported through study completion, an average of 1 year","Discharge status — Assessed at discharge and will be reported through study completion, an average of 1 year","Length of stay — Assessed from date of surgery until the date of discharge and will be reported through study completio…","30 day readmission — Assessed from date of discharge to thirty days after discharge and will be reported through study…"],"design_description":null,"source_has_results":false},"controlled_terms":["Thoracic","Thoracic Neoplasm","Lung Cancer","Esophageal Cancer","Surgery--Complications","Surgery","Sarcopenia","Malnutrition","Frail Elderly Syndrome","Frailty model"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct03413449","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2018-01-08 to 2024-11-08","comparator":null,"confidence":"structured-source","population":"ALL · 18 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.838Z","intervention":["Frailty model"],"participants":360,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Morbidity — Assessed at discharge and will be reported through study completion, an average of 1 year","Discharge status — Assessed at discharge and will be reported through study completion, an average of 1 year","Length of stay — Assessed from date of surgery until the date of discharge and will be reported through study completio…","30 day readmission — Assessed from date of discharge to thirty days after discharge and will be reported through study…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35503","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}