{"type":"trials","record":{"id":35514,"source_id":"clinicaltrials-gov","external_id":"NCT06658106","title":"Effect of Thera-Band Elastic Band-Assisted Progressive Resistance Training on Physical Health in Diabetes Patients with Frailty Syndrome","brief_summary":"Goal: The goal of this clinical trial is to evaluate the effectiveness of Thera-Band elastic band-assisted progressive resistance training (PRT) in improving physical health and reducing frailty in older adults with diabetes mellitus (DM) complicated by frailty syndrome (FS). Main Questions: Does Thera-Band elastic band-assisted PRT lower blood glucose levels in patients with DM? Does Thera-Band elastic band-assisted PRT improve physical function, as measured by handgrip strength and gait speed, in patients with FS? If there is a comparison group: Researchers will compare the Thera-Band elastic band PRT group to the conventional treatment group to see if the PRT intervention leads to greater improvements in physical health and frailty status. Participants will: Undergo Thera-Band elastic band-assisted progressive resistance training for 12 weeks, attending sessions three times a week. Complete assessments of their blood glucose levels and physical function before and after the intervention. Provide feedback on their fatigue, psychological state, and any adverse reactions during the training period.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Zhejiang Rongjun Hospital","enrollment":96,"countries":["China"],"start_date":"2023-04-01","completion_date":"2024-03-01","last_update_date":"2024-10-26","source_url":"https://clinicaltrials.gov/study/NCT06658106","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"60 Years","comparator":"Conventional Diabetes Management Group","organization":"Zhejiang Rongjun Hospital","interventions":["Thera-Band Elastic Band-Assisted Progressive Resistance Training","Conventional Diabetes Management"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Handgrip Strength — From enrollment to the end of treatment at 12 weeks.","Usual Gait Speed — From enrollment to the end of treatment at 12 weeks.","Short Physical Performance Battery — From enrollment to the end of treatment at 12 weeks.","Fasting Blood Glucose — From enrollment to the end of treatment at 12 weeks.","2-Hour Postprandial Blood Glucose — From enrollment to the end of treatment at 12 weeks.","Glycosylated Hemoglobin (HbA1c) — From enrollment to the end of treatment at 12 weeks.","FRAIL Scale — From enrollment to the end of treatment at 12 weeks.","Rating of Perceived Exertion — Assessed after each training session, three times per week, throughout the 12-week treat…","Geriatric Depression Scale-15 — From enrollment to the end of treatment at 12 weeks.","Diabetes Distress Scale — From enrollment to the end of treatment at 12 weeks."],"design_description":"RANDOMIZED · PARALLEL · SUPPORTIVE CARE · NONE","source_has_results":false},"controlled_terms":["Diabetes Mellitus","Thera-Band Elastic Band-Assisted Progressive Resistance Training","Conventional Diabetes Management"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: resistance training.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct06658106","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2023-04-01 to 2024-03-01","comparator":"Conventional Diabetes Management Group","confidence":"structured-source","population":"ALL · 60 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.537Z","intervention":["Thera-Band Elastic Band-Assisted Progressive Resistance Training","Conventional Diabetes Management"],"participants":96,"study_design":"RANDOMIZED · PARALLEL · SUPPORTIVE CARE · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Handgrip Strength — From enrollment to the end of treatment at 12 weeks.","Usual Gait Speed — From enrollment to the end of treatment at 12 weeks.","Short Physical Performance Battery — From enrollment to the end of treatment at 12 weeks.","Fasting Blood Glucose — From enrollment to the end of treatment at 12 weeks.","2-Hour Postprandial Blood Glucose — From enrollment to the end of treatment at 12 weeks.","Glycosylated Hemoglobin (HbA1c) — From enrollment to the end of treatment at 12 weeks.","FRAIL Scale — From enrollment to the end of treatment at 12 weeks.","Rating of Perceived Exertion — Assessed after each training session, three times per week, throughout the 12-week treat…","Geriatric Depression Scale-15 — From enrollment to the end of treatment at 12 weeks.","Diabetes Distress Scale — From enrollment to the end of treatment at 12 weeks."],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}},{"topic_slug":"resistance-training","is_published":true,"match_reasons":["Title contains controlled term: resistance training.","Abstract contains controlled term: resistance training.","Source terminology contains: resistance training.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Resistance training","slug":"resistance-training"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35514","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}