{"type":"trials","record":{"id":35572,"source_id":"clinicaltrials-gov","external_id":"NCT07575958","title":"Effects of Aquatic Exercise in Older Adults With Sarcopenia:A Randomized Trial","brief_summary":"Sarcopenia is a geriatric syndrome characterized by age-related loss of skeletal muscle mass, strength, and physical performance, leading to increased risk of falls, functional decline, and reduced quality of life. Exercise interventions, particularly resistance training, are effective in managing sarcopenia; however, land-based exercises may be challenging for older adults due to balance impairments, joint problems, and fear of falling. Pool-based exercise programs may offer a safe and feasible alternative, as water buoyancy reduces joint loading while providing resistance to support muscle strengthening. Despite these potential benefits, evidence regarding the effects of aquatic exercise in individuals with sarcopenia remains limited, especially in Türkiye. This study aims to evaluate the effects of a 6-week supervised pool-based exercise program on muscle strength, muscle morphology, physical performance, mood, and quality of life in individuals aged 65 years and older with sarcopenia. Sarcopenia will be identified using the Sonographic Thigh Adjustment Ratio (STAR), based on ultrasound measurements of anterior thigh muscle thickness. In addition, appendicular skeletal muscle mass will be assessed using bioelectrical impedance analysis (ASM/height²). Outcome measures will include ultrasound-based muscle thickness, STAR, muscle strength, functional performance tests, depressive symptoms, and health-related quality of life. Assessments will be performed at baseline, immediately after the intervention, and at 1-month follow-up.","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Gaziosmanpasa Research and Education Hospital","enrollment":44,"countries":["Turkey (Türkiye)"],"start_date":"2026-04-01","completion_date":"2026-12-01","last_update_date":"2026-08-18","source_url":"https://clinicaltrials.gov/study/NCT07575958","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:24.196666+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years","comparator":"Home Exercise Only Group","organization":"Gaziosmanpasa Research and Education Hospital","interventions":["Aquatic Exercise Program","Home Exercise Program"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Five Times Sit to Stand Test — Baseline, immediately after the 6-week intervention, and 1 month post-treatment follow-up","Sonographic Thigh Adjustment Ratio (STAR) — Baseline, immediately after the 6-week intervention, and 1 month post-treat…","Handgrip Strength — Baseline, immediately after the 6-week intervention, and 1 month post-treatment follow-up","Anterior Thigh Muscle Thickness — Baseline, immediately after the 6-week intervention, and 1 month post-treatment follo…","Appendicular Skeletal Muscle Mass Index (ASM/height²) — Baseline, immediately after the 6-week intervention, and 1 mont…","4-Meter Gait Speed Test — Baseline, immediately after the 6-week intervention, and 1 month post-treatment follow-up","Short Physical Performance Battery (SPPB) — Baseline, immediately after the 6-week intervention, and 1 month post-treat…","Berg Balance Scale — Baseline, immediately after the 6-week intervention, and 1 month post-treatment follow-up","Timed Up and Go (TUG) Test — Baseline, immediately after the 6-week intervention, and 1 month post-treatment follow-up","Geriatric Depression Scale (GDS) — Baseline, immediately after the 6-week intervention, and 1 month post-treatment foll…","SF-36 Quality of Life Scale — Baseline, immediately after the 6-week intervention, and 1 month post-treatment follow-up"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","source_has_results":false},"controlled_terms":["Sarcopenia","Sarcopenia in Elderly","Aquatic Exercise Program","Home Exercise Program"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct07575958","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2026-04-01 to 2026-12-01","comparator":"Home Exercise Only Group","confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.759Z","intervention":["Aquatic Exercise Program","Home Exercise Program"],"participants":44,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Five Times Sit to Stand Test — Baseline, immediately after the 6-week intervention, and 1 month post-treatment follow-up","Sonographic Thigh Adjustment Ratio (STAR) — Baseline, immediately after the 6-week intervention, and 1 month post-treat…","Handgrip Strength — Baseline, immediately after the 6-week intervention, and 1 month post-treatment follow-up","Anterior Thigh Muscle Thickness — Baseline, immediately after the 6-week intervention, and 1 month post-treatment follo…","Appendicular Skeletal Muscle Mass Index (ASM/height²) — Baseline, immediately after the 6-week intervention, and 1 mont…","4-Meter Gait Speed Test — Baseline, immediately after the 6-week intervention, and 1 month post-treatment follow-up","Short Physical Performance Battery (SPPB) — Baseline, immediately after the 6-week intervention, and 1 month post-treat…","Berg Balance Scale — Baseline, immediately after the 6-week intervention, and 1 month post-treatment follow-up","Timed Up and Go (TUG) Test — Baseline, immediately after the 6-week intervention, and 1 month post-treatment follow-up","Geriatric Depression Scale (GDS) — Baseline, immediately after the 6-week intervention, and 1 month post-treatment foll…","SF-36 Quality of Life Scale — Baseline, immediately after the 6-week intervention, and 1 month post-treatment follow-up"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Abstract contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35572","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}