{"type":"trials","record":{"id":35582,"source_id":"clinicaltrials-gov","external_id":"NCT07761091","title":"Effectiveness of Nutrition and Exercise Interventions in Older Adults With Sarcopenia in Can Gio District, Ho Chi Minh City","brief_summary":"Sarcopenia is an age-related condition characterized by progressive loss of muscle mass, muscle strength, and physical performance, which may adversely affect functional capacity and quality of life in older adults. This study is a three-arm, parallel-group randomized controlled trial designed to evaluate the effects of physical activity and combined physical activity plus nutritional support among community-dwelling older adults with sarcopenia. Eligible participants are randomly allocated in a 1:1:1 ratio to one of three groups: (1) a control group receiving health education, (2) a physical activity intervention group, or (3) a combined physical activity and nutritional support intervention group. Outcomes are assessed at baseline (T0), 3 months (T1), and 6 months (T2). The first 12 weeks evaluate the effects of the intervention, while weeks 13-24 evaluate the maintenance of intervention effects.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"University of Medicine and Pharmacy at Ho Chi Minh City","enrollment":90,"countries":["Vietnam"],"start_date":"2024-01-10","completion_date":"2025-12-31","last_update_date":"2026-08-12","source_url":"https://clinicaltrials.gov/study/NCT07761091","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:24.196666+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":"HMUIRB1078","age_range":"60 Years to 70 Years","comparator":"Control Group","organization":"University of Medicine and Pharmacy at Ho Chi Minh City","interventions":["Health education","Physical Activity Intervention","Individualized Nutritional Counseling","Oral nutritional supplementation"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Change in Skeletal Muscle Mass Index (SMI) from baseline to 6 months — Baseline (T0), 3 months (T1), and 6 months (T2);…","Change in Handgrip Strength From Baseline to 6 Months — Baseline (T0), 3 months (T1), and 6 months (T2)","Change in Gait Speed — Baseline, 3 months, and 6 months","Change in Nutritional Status Assessed by the Mini Nutritional Assessment — Baseline (T0), 3 months (T1), and 6 months (…","Change in Dietary Energy, Protein Intake — Baseline (T0), 3 months (T1), and 6 months (T2)","Change in Quality of Life — Baseline (T0), 3 months (T1), and 6 months (T2)"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Sarcopenia","Health education","Physical Activity Intervention","Individualized Nutritional Counseling","Oral nutritional supplementation"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct07761091","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2024-01-10 to 2025-12-31","comparator":"Control Group","confidence":"structured-source","population":"ALL · 60 Years to 70 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.761Z","intervention":["Health education","Physical Activity Intervention","Individualized Nutritional Counseling","Oral nutritional supplementation"],"participants":90,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Change in Skeletal Muscle Mass Index (SMI) from baseline to 6 months — Baseline (T0), 3 months (T1), and 6 months (T2);…","Change in Handgrip Strength From Baseline to 6 Months — Baseline (T0), 3 months (T1), and 6 months (T2)","Change in Gait Speed — Baseline, 3 months, and 6 months","Change in Nutritional Status Assessed by the Mini Nutritional Assessment — Baseline (T0), 3 months (T1), and 6 months (…","Change in Dietary Energy, Protein Intake — Baseline (T0), 3 months (T1), and 6 months (T2)","Change in Quality of Life — Baseline (T0), 3 months (T1), and 6 months (T2)"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Abstract contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35582","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}