{"type":"trials","record":{"id":35745,"source_id":"clinicaltrials-gov","external_id":"NCT07538674","title":"Peiyuan Guben Tongluo Ointment for Elderly Sarcopenia","brief_summary":"With the agarose concentrating group of Peiyuan Guben Tongluo Ointment set as the parallel control and an external control established simultaneously, this study aimed to evaluate the increases from baseline in DXA-measured limb muscle mass after 12 weeks of medication in elderly sarcopenia patients treated with the Ejiao concentrating group of Peiyuan Guben Tongluo Ointment.","overall_status":"Not Yet Recruiting","phases":["PHASE2"],"study_type":"INTERVENTIONAL","sponsor":"Shanghai Yueyang Integrated Medicine Hospital","enrollment":60,"countries":["China"],"start_date":"2026-04-01","completion_date":"2028-12-31","last_update_date":"2026-04-20","source_url":"https://clinicaltrials.gov/study/NCT07538674","editorial_summary":"A registered PHASE2 study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:24.196666+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"60 Years to 80 Years","comparator":"Peiyuan Guben Tongluo Ointment (Agarose concentrated)","organization":"Shanghai Yueyang Integrated Medicine Hospital","interventions":["nutritional intervention","Exercise","Peiyuan Guben Tongluo Ointment (Ejiao concentrated)","Peiyuan Guben Tongluo Ointment (Agarose concentrated)"],"registry_source":"ClinicalTrials.gov","outcome_measures":["DXA-measured appendicular skeletal muscle mass — Baseline, week 12, week 24","Upper limb handgrip strength — Up to 24 weeks","Handgrip strength — Baseline, week 12, week 24","Timed Up and Go test (TUG) — Baseline, week 12, week 24","Berg Balance Scale (BBS) — Baseline, week 12, week 24","TCM Syndrome Score — Baseline, week 12, week 24","Peripheral blood white blood cell count — Baseline, week 12","Neutrophil count — Baseline, week 12","Interleukin-2 — Baseline, week 12","Interleukin-6 — Baseline, week 12","Mini Nutritional Assessment (MNA) — Baseline, week 12, week 24","Activities of Daily Living (ADL) Scale — Baseline. week 12, week 24"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · DOUBLE","source_has_results":false},"controlled_terms":["Sarcopenia in Elderly","nutritional intervention","Exercise","Peiyuan Guben Tongluo Ointment (Ejiao concentrated)","Peiyuan Guben Tongluo Ointment (Agarose concentrated)"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct07538674","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2026-04-01 to 2028-12-31","comparator":"Peiyuan Guben Tongluo Ointment (Agarose concentrated)","confidence":"structured-source","population":"ALL · 60 Years to 80 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.787Z","intervention":["nutritional intervention","Exercise","Peiyuan Guben Tongluo Ointment (Ejiao concentrated)","Peiyuan Guben Tongluo Ointment (Agarose concentrated)"],"participants":60,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · DOUBLE","subject_scope":"Human clinical study registration","evidence_stage":"PHASE2","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["DXA-measured appendicular skeletal muscle mass — Baseline, week 12, week 24","Upper limb handgrip strength — Up to 24 weeks","Handgrip strength — Baseline, week 12, week 24","Timed Up and Go test (TUG) — Baseline, week 12, week 24","Berg Balance Scale (BBS) — Baseline, week 12, week 24","TCM Syndrome Score — Baseline, week 12, week 24","Peripheral blood white blood cell count — Baseline, week 12","Neutrophil count — Baseline, week 12","Interleukin-2 — Baseline, week 12","Interleukin-6 — Baseline, week 12","Mini Nutritional Assessment (MNA) — Baseline, week 12, week 24","Activities of Daily Living (ADL) Scale — Baseline. week 12, week 24"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Abstract contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: elderly.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35745","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}