{"type":"trials","record":{"id":35776,"source_id":"clinicaltrials-gov","external_id":"NCT07398495","title":"Multimodal Training Effects in Middle-Aged and Older Adults With Diabetic Sarcopenia","brief_summary":"This study aims to investigate the effects of a 12-week multimodal exercise intervention on middle-aged and older adults (aged 45\\~85 years) with Type 2 Diabetes Mellitus (T2DM). The program combines supervised training, home-based sessions, and digital support to improve muscle function, physical performance, metabolic control, and quality of life.","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"yueh chu wu","enrollment":128,"countries":["Taiwan"],"start_date":"2026-02-23","completion_date":"2026-08-15","last_update_date":"2026-03-30","source_url":"https://clinicaltrials.gov/study/NCT07398495","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:24.196666+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"45 Years to 85 Years","comparator":"Control Group (Standard Care)","organization":"Chung Shan Medical University","interventions":["Multimodal Exercise Program"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Physical Function (5TSTS) — Change from Baseline at Week 12 and Week 24","Handgrip Strength (HGS) — Change from Baseline at Week 12 and Week 24","Skeletal Muscle Mass Index (SMI) — Change from Baseline at Week 12 and Week 24","Sarcopenia Risk: Assessed using the Strength, Assistance with walking, Rise from a chair, Climb stairs, and Falls (SARC…","Glycated Hemoglobin (HbA1c) — Change from Baseline at Week 12 and Week 24","Quality of Life (SF-12) — Change from Baseline at Week 12 and Week 24"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","source_has_results":false},"controlled_terms":["Type 2 Diabetes Mellitus (T2DM)","Sarcopenia","Multimodal Exercise Program"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct07398495","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2026-02-23 to 2026-08-15","comparator":"Control Group (Standard Care)","confidence":"structured-source","population":"ALL · 45 Years to 85 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.792Z","intervention":["Multimodal Exercise Program"],"participants":128,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Physical Function (5TSTS) — Change from Baseline at Week 12 and Week 24","Handgrip Strength (HGS) — Change from Baseline at Week 12 and Week 24","Skeletal Muscle Mass Index (SMI) — Change from Baseline at Week 12 and Week 24","Sarcopenia Risk: Assessed using the Strength, Assistance with walking, Rise from a chair, Climb stairs, and Falls (SARC…","Glycated Hemoglobin (HbA1c) — Change from Baseline at Week 12 and Week 24","Quality of Life (SF-12) — Change from Baseline at Week 12 and Week 24"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35776","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}