{"type":"trials","record":{"id":35805,"source_id":"clinicaltrials-gov","external_id":"NCT07454759","title":"Acute Sarcopenia in Hospitalized Older Adults","brief_summary":"Acute sarcopenia is a rapid decline in muscle mass and function occurring within 28 days of a major stressor, such as hospitalization, infection, or surgery. It is frequent but often underdiagnosed in older adult. Current standard of care lacks systematic strategies for its early detection and risk stratification. This study therefore proposes to combine established clinical and instrumental assessments (handgrip dynamometry, bioelectrical impedance analysis, ultrasound of the anterior thigh) to better characterize the risk factors, and outcomes of acute sarcopenia in hospitalized patients aged 65 years or older. The study hypothesis is that the use of a systematic objective clinical assessments will improve early detection and risk stratification of this condition and the detection of acute sarcopenia related outcomes. This is a prospective observational cohort study that will be conducted in the Emergency Department and Medical Wards of the San Raffaele Hospital. Studies objectives will include: * Determination of the incidence of acute sarcopenia * Identification of clinical and demographic risk factors for acute sarcopenia and relevant clinical outcomes associated with this condition","overall_status":"Not Yet Recruiting","phases":[],"study_type":"OBSERVATIONAL","sponsor":"IRCCS San Raffaele","enrollment":280,"countries":[],"start_date":"2026-06-01","completion_date":"2027-05-01","last_update_date":"2026-03-06","source_url":"https://clinicaltrials.gov/study/NCT07454759","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:24.196666+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":"BASIS","age_range":"65 Years","comparator":null,"organization":"IRCCS San Raffaele","interventions":["Acute sarcopenia will be defined as the incidence of sarcopenia compared to baseline measurements at recruitment, using…"],"registry_source":"ClinicalTrials.gov","outcome_measures":["ACUTE SARCOPENIA INCIDENCE — Time point(s): baseline (within 24h of admission), days 3, 5, 7, 10, then every 5 days unt…","ACUTE SARCOPENIA RISK FACTORS AND OUTCOMES — Time point(s): baseline (within 24h of admission), days 3, 5, 7, 10, every…"],"design_description":null,"source_has_results":false},"controlled_terms":["Sarcopenia","Sarcopenia in Elderly","Acute sarcopenia will be defined as the incidence of sarcopenia compared to baseline measurements at recruitment, using…"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct07454759","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2026-06-01 to 2027-05-01","comparator":null,"confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.796Z","intervention":["Acute sarcopenia will be defined as the incidence of sarcopenia compared to baseline measurements at recruitment, using…"],"participants":280,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["ACUTE SARCOPENIA INCIDENCE — Time point(s): baseline (within 24h of admission), days 3, 5, 7, 10, then every 5 days unt…","ACUTE SARCOPENIA RISK FACTORS AND OUTCOMES — Time point(s): baseline (within 24h of admission), days 3, 5, 7, 10, every…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Abstract contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: older adult.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35805","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}