{"type":"trials","record":{"id":35858,"source_id":"clinicaltrials-gov","external_id":"NCT07309120","title":"Nutrition Ameliorates the Muscle Loss of Pre-sarcopenia in Elderly","brief_summary":"This study evaluates the effects of a 12-week leucine-enriched protein supplementation in adults aged 60 years and more. Participants will undergo assessments of muscle mass and function, as well as metabolic profiles in blood, urine, and feces before and after the intervention.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Chang Gung Memorial Hospital","enrollment":60,"countries":["Taiwan"],"start_date":"2021-12-24","completion_date":"2023-06-20","last_update_date":"2026-01-08","source_url":"https://clinicaltrials.gov/study/NCT07309120","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:24.196666+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"60 Years to 90 Years","comparator":null,"organization":"Chang Gung Memorial Hospital","interventions":["Participants consume two sachets daily over a 12-week intervention period."],"registry_source":"ClinicalTrials.gov","outcome_measures":["Appendicular Skeletal Muscle Index (ASMI) — Baseline and 12 weeks after intervention","Handgrip Strength (HGS) — Baseline and 12 weeks after intervention","Gait speed (m/s) — Baseline and 12 weeks after intervention"],"design_description":"NA · SINGLE GROUP · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Low Muscle Mass","Low Muscle Strength","Low Physical Function","Participants consume two sachets daily over a 12-week intervention period."],"relevance_confidence":80,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct07309120","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2021-12-24 to 2023-06-20","comparator":null,"confidence":"structured-source","population":"ALL · 60 Years to 90 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.804Z","intervention":["Participants consume two sachets daily over a 12-week intervention period."],"participants":60,"study_design":"NA · SINGLE GROUP · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Appendicular Skeletal Muscle Index (ASMI) — Baseline and 12 weeks after intervention","Handgrip Strength (HGS) — Baseline and 12 weeks after intervention","Gait speed (m/s) — Baseline and 12 weeks after intervention"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Title supplies longevity context: elderly.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","title context","study type"],"relevance_score":80,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35858","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}