{"type":"trials","record":{"id":35986,"source_id":"clinicaltrials-gov","external_id":"NCT06986395","title":"Blood Flow Restriction Training for Age-Related Sarcopenia","brief_summary":"Brief Title: Safe Exercise for Age-Related Muscle Loss in Hospitalized Seniors Summary: This study compares two exercise methods to help older hospital patients (age 65+) rebuild muscle strength after being diagnosed with sarcopenia (age-related muscle loss). We want to know if using special pressure cuffs during light exercise works better than traditional strength training alone. Who Can Join: Hospitalized seniors with stable health conditions Excludes those with severe disabilities, dementia, or certain blood circulation problems What We'll Do: 40 participants will be randomly assigned to either: Traditional Training Group: Uses weights/bands at 65-75% max capacity Arm/leg exercises 3x/week for 4 weeks Pressure Cuff Training Group: Uses special cuffs on arms/thighs during lighter exercises (20% max capacity) Same exercise frequency with controlled pressure for safety What We'll Measure: Handgrip strength (main test at 0/4/12 weeks) Walking speed, balance tests, quality of life surveys Any side effects like dizziness/nausea Safety First: Doctors will check your health before starting. Nurses will monitor every session. We use medical-grade cuffs with safe pressure limits (arm: 80-100mmHg, thigh: 150-200mmHg). You can stop anytime if uncomfortable. Why This Matters: This could help hospitalized seniors regain strength faster using gentler exercises. All activities are supervised by rehabilitation specialists at West China Hospital, with ethics committee approval (IRB number required).","overall_status":"Not Yet Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"West China Hospital","enrollment":40,"countries":[],"start_date":"2025-05-01","completion_date":"2025-09-10","last_update_date":"2025-05-23","source_url":"https://clinicaltrials.gov/study/NCT06986395","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:24.196666+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years to 100 Years","comparator":"CRT Group","organization":"West China Hospital","interventions":["Blood Flow Restriction Training (BFRT)","Conventional Resistance Training (CRT)"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Change in Handgrip Strength — Baseline (Week 0), Post-intervention (Week 4), Follow-up (Week 12)","6-Meter Walking Speed — Baseline (Week 0), Follow-up (Week 12)","Short Physical Performance Battery (SPPB) — Baseline (Week 0), Post-intervention (Week 4), Follow-up (Week 12)","Timed Up and Go Test (TUG) — Baseline (Week 0), Post-intervention (Week 4), Follow-up (Week 12)","MBI — Baseline (Week 0), Post-intervention (Week 4), Follow-up (Week 12)"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","source_has_results":false},"controlled_terms":["Sarcopenia in Elderly","Blood Flow Restriction Training (BFRT)","Conventional Resistance Training (CRT)"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct06986395","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-05-01 to 2025-09-10","comparator":"CRT Group","confidence":"structured-source","population":"ALL · 65 Years to 100 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.823Z","intervention":["Blood Flow Restriction Training (BFRT)","Conventional Resistance Training (CRT)"],"participants":40,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Change in Handgrip Strength — Baseline (Week 0), Post-intervention (Week 4), Follow-up (Week 12)","6-Meter Walking Speed — Baseline (Week 0), Follow-up (Week 12)","Short Physical Performance Battery (SPPB) — Baseline (Week 0), Post-intervention (Week 4), Follow-up (Week 12)","Timed Up and Go Test (TUG) — Baseline (Week 0), Post-intervention (Week 4), Follow-up (Week 12)","MBI — Baseline (Week 0), Post-intervention (Week 4), Follow-up (Week 12)"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Abstract contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: age-related.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/35986","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}