{"type":"trials","record":{"id":36280,"source_id":"clinicaltrials-gov","external_id":"NCT05705934","title":"Investigation of The Effects of Holistic Group Exercise Program on Muscle Thickness and Physical Performance in Older Adults With Sarcopenia","brief_summary":"A decrease in muscle mass and function can cause the development of many chronic diseases, including sarcopenia. It has been reported that the best intervention for sarcopenia is exercise. Despite this, the optimal type of exercise for sarcopenia has not yet been determined. Although the holistic approach is used in the literature in the elderly population, it is noticeable that it does not find much space for itself in this patient group. In this study, it was aimed to examine the effects of holistic approach-based exercise program on individuals with sarcopenia.","overall_status":"Unknown","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Ondokuz Mayıs University","enrollment":34,"countries":[],"start_date":"2023-03-30","completion_date":"2024-11-30","last_update_date":"2023-01-31","source_url":"https://clinicaltrials.gov/study/NCT05705934","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:24.196666+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years to 105 Years","comparator":"Group 2","organization":"Ondokuz Mayıs University","interventions":["Exercise"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Muscle Mass — Change from baseline at 12 weeks","The Timed Up&Go Test — Change from baseline at 12 weeks","Short Physical Performance Battery (SPPB) — Change from baseline at 12 weeks","SARC-F Questionnaire — Change from baseline at 12 weeks","Charlson Comorbidity Index — Change from baseline at 12 weeks","30-Second Chair Stand Test — Change from baseline at 12 weeks","Hand Grip Strength — Change from baseline at 12 weeks","Berg Balance Test — Change from baseline at 12 weeks","Depression — Change from baseline at 12 weeks","Mini Nutritional Assessment (MNA) — Change from baseline at 12 weeks"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","source_has_results":false},"controlled_terms":["Sarcopenia","Exercise"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct05705934","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2023-03-30 to 2024-11-30","comparator":"Group 2","confidence":"structured-source","population":"ALL · 65 Years to 105 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.864Z","intervention":["Exercise"],"participants":34,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Muscle Mass — Change from baseline at 12 weeks","The Timed Up&Go Test — Change from baseline at 12 weeks","Short Physical Performance Battery (SPPB) — Change from baseline at 12 weeks","SARC-F Questionnaire — Change from baseline at 12 weeks","Charlson Comorbidity Index — Change from baseline at 12 weeks","30-Second Chair Stand Test — Change from baseline at 12 weeks","Hand Grip Strength — Change from baseline at 12 weeks","Berg Balance Test — Change from baseline at 12 weeks","Depression — Change from baseline at 12 weeks","Mini Nutritional Assessment (MNA) — Change from baseline at 12 weeks"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Abstract contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/36280","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}