{"type":"trials","record":{"id":36348,"source_id":"clinicaltrials-gov","external_id":"NCT05224453","title":"Integrated Physical Training With Protein Diet in Older Adults With Sarcopenia Symptoms.","brief_summary":"Sarcopenia is the major health concern and common consequence of COVID-19 in the aging population. Moreover, this clinical condition has not been considered in usual physical rehabilitation practice, and its optimal protein requirement in food is not well defined, which requires a meaningful study in this field. The reports of this trial would deliver the latest evidence and proper guidelines for the prescription of physical exercises and also provide an optimal dietary plan in sarcopenia patients with COVID infection. Objective: To find and compare the clinical and psychological effects of integrated physical training with a high protein diet versus a low-protein diet in community-dwelling COVID-19 asymptomatic older adults with Sarcopenia symptoms.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Prince Sattam Bin Abdulaziz University","enrollment":76,"countries":["Saudi Arabia"],"start_date":"2020-03-01","completion_date":"2021-11-30","last_update_date":"2022-02-17","source_url":"https://clinicaltrials.gov/study/NCT05224453","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:24.196666+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"MALE","acronym":null,"age_range":"60 Years to 80 Years","comparator":null,"organization":"Prince Sattam Bin Abdulaziz University","interventions":["Physical training and high protein diet","Physical training and low protein diet"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Changes in Hand Grip Strength — At baseline and at 6 months","Change in Muscle Cross Sectional Area — At baseline and at 6 months","Changes in Kinesiophobia — At baseline and at 6 months","Changes in Quality of Life — At baseline and at 6 months"],"design_description":"RANDOMIZED · PARALLEL · HEALTH SERVICES RESEARCH · SINGLE","source_has_results":true},"controlled_terms":["Sarcopenia","Physical training and high protein diet","Physical training and low protein diet"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct05224453","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2020-03-01 to 2021-11-30","comparator":null,"confidence":"structured-source","population":"MALE · 60 Years to 80 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.873Z","intervention":["Physical training and high protein diet","Physical training and low protein diet"],"participants":76,"study_design":"RANDOMIZED · PARALLEL · HEALTH SERVICES RESEARCH · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Changes in Hand Grip Strength — At baseline and at 6 months","Change in Muscle Cross Sectional Area — At baseline and at 6 months","Changes in Kinesiophobia — At baseline and at 6 months","Changes in Quality of Life — At baseline and at 6 months"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Abstract contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/36348","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}