{"type":"trials","record":{"id":36374,"source_id":"clinicaltrials-gov","external_id":"NCT05035121","title":"Effect of Nutrition Supplementation Combined With Resistance Exercise in Elderly With Sarcopenia.","brief_summary":"The purpose of this study was determine whether milk or soy milk supplements combined with resistance exercise improved sarcopenia in the elderly. This study was randomized controlled trail that recruited elderly people ≧65 years old with sarcopenia in the nursing home of Taipei Veterans General Hospital Su-Ao and Yuanshan Branch from June 2017 to December, 2017. The participants were divided into three groups, such as control, milk supplement and soy milk supplement. The milk and soy milk groups provided 200 mL milk or soy milk two times per day. Moreover, all participants joined the resistance exercise training program, three times per week (30 min/time). After 12 weeks, the anthropometry, sarcopenia index, blood biochemical index, nutrition status index, inflammation index, insulin resistance index, and dietary intake were measured.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Taipei Medical University","enrollment":35,"countries":["Taiwan"],"start_date":"2017-03-24","completion_date":"2018-03-23","last_update_date":"2021-09-05","source_url":"https://clinicaltrials.gov/study/NCT05035121","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:24.196666+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years to 99 Years","comparator":"control","organization":"Taipei Medical University","interventions":["milk supplement","soy milk supplement","resistance exercise"],"registry_source":"ClinicalTrials.gov","outcome_measures":["appendicular skeletal muscle mass in kilograms — baseline","Change from baseline appendicular skeletal muscle mass at 6 weeks — 6 weeks","Change from baseline appendicular skeletal muscle mass at 12 weeks — 12 weeks","height in meters — baseline","Change baseline weeks height at 6 weeks — 6 weeks","Change from baseline height at 12 weeks — 12 weeks","appendicular skeletal muscle mass index in kg/m^2 — baseline","Change from baseline appendicular skeletal muscle mass index at 6 weeks — 6 weeks","Change from baseline appendicular skeletal muscle mass index at 12 weeks — 12 weeks","calf circumferences in centimeter — baseline","Change from baseline calf circumferences at 6 weeks — 6 weeks","Change from baseline calf circumferences at 12 weeks — 12 weeks","hand grip in kilograms — baseline","Change from baseline hand grip at 6 weeks — 6 weeks","Change from baseline hand grip at 12 weeks — 12 weeks","gait speed in meter per second — baseline","Change from baseline gait speed at 6 weeks — 6 weeks","Change from baseline gait speed at 12 weeks — 12 weeks","blood alanine transaminase activity in U/L — baseline","Change from baseline blood alanine transaminase activity at 12 weeks — 12 weeks"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · DOUBLE","source_has_results":false},"controlled_terms":["Sarcopenia","milk supplement","soy milk supplement","resistance exercise"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct05035121","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2017-03-24 to 2018-03-23","comparator":"control","confidence":"structured-source","population":"ALL · 65 Years to 99 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.877Z","intervention":["milk supplement","soy milk supplement","resistance exercise"],"participants":35,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · DOUBLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["appendicular skeletal muscle mass in kilograms — baseline","Change from baseline appendicular skeletal muscle mass at 6 weeks — 6 weeks","Change from baseline appendicular skeletal muscle mass at 12 weeks — 12 weeks","height in meters — baseline","Change baseline weeks height at 6 weeks — 6 weeks","Change from baseline height at 12 weeks — 12 weeks","appendicular skeletal muscle mass index in kg/m^2 — baseline","Change from baseline appendicular skeletal muscle mass index at 6 weeks — 6 weeks","Change from baseline appendicular skeletal muscle mass index at 12 weeks — 12 weeks","calf circumferences in centimeter — baseline","Change from baseline calf circumferences at 6 weeks — 6 weeks","Change from baseline calf circumferences at 12 weeks — 12 weeks","hand grip in kilograms — baseline","Change from baseline hand grip at 6 weeks — 6 weeks","Change from baseline hand grip at 12 weeks — 12 weeks","gait speed in meter per second — baseline","Change from baseline gait speed at 6 weeks — 6 weeks","Change from baseline gait speed at 12 weeks — 12 weeks","blood alanine transaminase activity in U/L — baseline","Change from baseline blood alanine transaminase activity at 12 weeks — 12 weeks"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Abstract contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: elderly.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/36374","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}