{"type":"trials","record":{"id":36442,"source_id":"clinicaltrials-gov","external_id":"NCT03862937","title":"Effect of Protein Consumption and Resistance Training on Body Composition, Muscular Strength and Functional Capacity in the Elderly","brief_summary":"The increase in life expectancy of the world population is associated with a higher incidence of diseases, leading to functional incapacity and dependence in old age. Aging is usually accompanied by progressive loss of muscle mass, muscular strength and functional capacity, possibly exacerbated by inactivity and low protein and energy consumption of elderly individuals. However, the response to strength training, as well as the daily recommendation of protein and other factors related to sarcopenia in this population seem not to be well understood. Objective: To evaluate the effect of protein intake and resistance training on body composition, muscle strength and functional capacity in the elderly. METHODS: A randomized placebo-controlled clinical trial will be conducted with 38 elderly people, ≥ 60 years old, sedentary, and body mass index between 22 and 30 kg / m2. All those who agree to participate will be randomized into two groups (intervention or placebo) and will undergo an initial assessment consisting of food consumption analysis through the application of the three-day food record, assessment of muscle thickness of the thigh and arm by muscle ultrasonography, evaluation of body composition by dual energy X-ray absorptiometry (DEXA), dynamic maximal strength (1RM) test of knee extension and elbow flexion, peak torque test of knee extension, functional capacity tests and quality of life questionnaire (SF-36). The elderly will participate in resistance training for 12 weeks, two session per week. The intervention group will be supplemented with whey protein isolate (2x / day - 20g for breakfast and 20g for dinner) and the placebo group will receive maltodextrin (2x / day - 20g for breakfast and 20g for dinner). All outcomes will be assessed before and after the 12-week resistance training period.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Federal University of Health Science of Porto Alegre","enrollment":38,"countries":["Brazil"],"start_date":"2019-03-03","completion_date":"2019-12-20","last_update_date":"2020-07-21","source_url":"https://clinicaltrials.gov/study/NCT03862937","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:24.196666+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"60 Years to 80 Years","comparator":"Placebo","organization":"Federal University of Health Science of Porto Alegre","interventions":["Exercise training + whey protein","Exercise training + placebo (maltodextrin)"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Densitometry by dual energy X-ray absorptiometry (DEXA) change from baseline. — This measure will be performed before a…","Ultrasonography change from baseline. — This measure will be performed before and after the intervention (12 weeks resi…","Muscular strength (peak of torque) change from baseline. — This measure will be performed before and after the interven…","Muscular strength (1-RM) change from baseline. — This measure will be performed before and after the intervention (12 w…","Functional capacity (sit and stand up test) change from baseline. — This measure will be performed before and after the…","Functional capacity (timed up and go test) change from baseline. — This measure will be performed before and after the…","Functional capacity (stair climbing test) change from baseline. — This measure will be performed before and after the i…","Protein intake (dietary record) baseline. — To evaluate the food consumption will be used the dietary record of three d…","Protein intake (24-hour food recall). — To verify possible changes in dietary intake over the 12 weeks of intervention,…","Diet Quality Index. — To evaluate the quality of the diet will be used the Healthy Eating Index (HEI) that assigns scor…","Quality of life (SF-36) change from baseline. — This measure will be performed before and after the intervention (12-we…"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · DOUBLE","source_has_results":false},"controlled_terms":["Elderly","Sarcopenia","Exercise training + whey protein","Exercise training + placebo (maltodextrin)"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: resistance training.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct03862937","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2019-03-03 to 2019-12-20","comparator":"Placebo","confidence":"structured-source","population":"ALL · 60 Years to 80 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.885Z","intervention":["Exercise training + whey protein","Exercise training + placebo (maltodextrin)"],"participants":38,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · DOUBLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Densitometry by dual energy X-ray absorptiometry (DEXA) change from baseline. — This measure will be performed before a…","Ultrasonography change from baseline. — This measure will be performed before and after the intervention (12 weeks resi…","Muscular strength (peak of torque) change from baseline. — This measure will be performed before and after the interven…","Muscular strength (1-RM) change from baseline. — This measure will be performed before and after the intervention (12 w…","Functional capacity (sit and stand up test) change from baseline. — This measure will be performed before and after the…","Functional capacity (timed up and go test) change from baseline. — This measure will be performed before and after the…","Functional capacity (stair climbing test) change from baseline. — This measure will be performed before and after the i…","Protein intake (dietary record) baseline. — To evaluate the food consumption will be used the dietary record of three d…","Protein intake (24-hour food recall). — To verify possible changes in dietary intake over the 12 weeks of intervention,…","Diet Quality Index. — To evaluate the quality of the diet will be used the Healthy Eating Index (HEI) that assigns scor…","Quality of life (SF-36) change from baseline. — This measure will be performed before and after the intervention (12-we…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"resistance-training","is_published":true,"match_reasons":["Title contains controlled term: resistance training.","Abstract contains controlled term: resistance training, strength training.","Title supplies longevity context: elderly.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Resistance training","slug":"resistance-training"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/36442","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}