{"type":"trials","record":{"id":39425,"source_id":"clinicaltrials-gov","external_id":"NCT07372001","title":"Effects on Facial Skin Aging After Topical Application of Exosomes With a Microneedling Device","brief_summary":"In this study, we evaluated the extent of reversal of facial dermal aging signs using topical lyophilized exosomes with a microneedling device","overall_status":"Completed","phases":["PHASE4"],"study_type":"INTERVENTIONAL","sponsor":"Instituto de Oftalmología Fundación Conde de Valenciana","enrollment":30,"countries":["Mexico"],"start_date":"2024-07-01","completion_date":"2025-03-01","last_update_date":"2026-01-28","source_url":"https://clinicaltrials.gov/study/NCT07372001","editorial_summary":"A registered PHASE4 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:19.060264+00:00","last_seen_at":"2026-09-25T06:20:14.553+00:00","metadata":{"sex":"ALL","acronym":"EFSATAEMD","age_range":"50 Years","comparator":null,"organization":"Instituto de Oftalmología Fundación Conde de Valenciana","interventions":["Topical lyophilized exosomes application"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Facial dermal changes — From enrollment to the end of treatment at 8 weeks","Subjective evaluation of facial dermal changes — From enrollment to the end of treatment at 8 weeks"],"design_description":"NA · SINGLE GROUP · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Skin Aging","Topical lyophilized exosomes application"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: skin aging.","quality_checked_at":"2026-09-25T06:20:17.523592+00:00","duplicate_cluster_key":"id:nct07372001","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2024-07-01 to 2025-03-01","comparator":null,"confidence":"structured-source","population":"ALL · 50 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:14.568Z","intervention":["Topical lyophilized exosomes application"],"participants":30,"study_design":"NA · SINGLE GROUP · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"PHASE4","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Facial dermal changes — From enrollment to the end of treatment at 8 weeks","Subjective evaluation of facial dermal changes — From enrollment to the end of treatment at 8 weeks"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"skin-aging","is_published":true,"match_reasons":["Title contains controlled term: skin aging.","Source terminology contains: skin aging.","Title supplies longevity context: aging.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Skin ageing","slug":"skin-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/39425","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}