{"type":"trials","record":{"id":39448,"source_id":"clinicaltrials-gov","external_id":"NCT07156071","title":"12-Week Study on the Efficacy of Two Serums in Improving Skin Aging and Tone","brief_summary":"This study aims to evaluate the anti-aging and skin tone improvement effects of two facial serums over a 12-week period. It was conducted at a single research center with a 2-week washout period followed by full-face application of the test products for 12 weeks. A total of at least 120 healthy Chinese female participants aged 18 to 45 were enrolled and divided into two treatment groups:Each group included both early aging (18-29 years) and mature aging (30-45 years) subgroups, with at least 30 participants in each subgroup.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"ChinaNorm","enrollment":120,"countries":["China"],"start_date":"2023-11-18","completion_date":"2024-03-22","last_update_date":"2025-09-08","source_url":"https://clinicaltrials.gov/study/NCT07156071","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:19.060264+00:00","last_seen_at":"2026-09-25T06:20:14.553+00:00","metadata":{"sex":"FEMALE","acronym":null,"age_range":"18 Years to 45 Years","comparator":null,"organization":"ChinaNorm","interventions":["Serum 1","Serum 2"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Change in Dermatologist-Assessed Wrinkle Attributes — from Baseline to Week 12","Self-assessment Questionnaire — 12 weeks","Change in Dermatologist-Assessed Skin Texture and Quality Attributes — from Baseline to Week 12","Change in Dermatologist-Assessed Skin Tone Attributes — from Baseline to Week 12","Change in Skin Hydration Measured by Corneometer — 12 weeks","Change in Skin Elasticity Measured by Cutometer — 12 weeks","Change in Transepidermal Water Loss (TEWL) Measured by Vapometer — 12 weeks","Change in Facial Image-Based Skin Parameters Using VISIA-CR — 12 weeks","Change in Cheek Skin Surface Condition Using VisioScan VC20 — 12 weeks"],"design_description":"NA · PARALLEL · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Facial Skin Aging and Dullness","Serum 1","Serum 2"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: skin aging.","quality_checked_at":"2026-09-25T06:20:17.523592+00:00","duplicate_cluster_key":"id:nct07156071","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2023-11-18 to 2024-03-22","comparator":null,"confidence":"structured-source","population":"FEMALE · 18 Years to 45 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:14.572Z","intervention":["Serum 1","Serum 2"],"participants":120,"study_design":"NA · PARALLEL · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Change in Dermatologist-Assessed Wrinkle Attributes — from Baseline to Week 12","Self-assessment Questionnaire — 12 weeks","Change in Dermatologist-Assessed Skin Texture and Quality Attributes — from Baseline to Week 12","Change in Dermatologist-Assessed Skin Tone Attributes — from Baseline to Week 12","Change in Skin Hydration Measured by Corneometer — 12 weeks","Change in Skin Elasticity Measured by Cutometer — 12 weeks","Change in Transepidermal Water Loss (TEWL) Measured by Vapometer — 12 weeks","Change in Facial Image-Based Skin Parameters Using VISIA-CR — 12 weeks","Change in Cheek Skin Surface Condition Using VisioScan VC20 — 12 weeks"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"skin-aging","is_published":true,"match_reasons":["Title contains controlled term: skin aging.","Source terminology contains: skin aging.","Title supplies longevity context: aging.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Skin ageing","slug":"skin-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/39448","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}