{"type":"trials","record":{"id":39531,"source_id":"clinicaltrials-gov","external_id":"NCT06146140","title":"Effects of an Oral Herbal Supplement on Skin Aging, Hydration, and Elasticity","brief_summary":"The purpose of this study is to evaluate how an oral herbal supplementation influences facial skin elasticity and facial hydration as well as markers of photoaging (erythema and pigmentation).","overall_status":"Unknown","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Integrative Skin Science and Research","enrollment":36,"countries":[],"start_date":"2023-12-01","completion_date":"2024-12-01","last_update_date":"2023-11-24","source_url":"https://clinicaltrials.gov/study/NCT06146140","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:19.060264+00:00","last_seen_at":"2026-09-25T06:20:14.553+00:00","metadata":{"sex":"FEMALE","acronym":null,"age_range":"35 Years to 55 Years","comparator":"Oral Placebo Supplement","organization":"Integrative Skin Science and Research","interventions":["Oral herbal supplement","Oral placebo supplement"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Change in Skin Elasticity — 8 weeks","Change in Skin Hydration — 8 weeks","Change in skin pigmentation intensity — 8 weeks","Change in appearance of facial wrinkles — 8 weeks","Change in the skin erythema — 8 weeks","Change in skin transepidermal water loss — 8 weeks","Self-perception of skin (changes in facial fine lines and wrinkles, firmness, etc) — 8 weeks","Product Tolerability — 8 weeks"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · TRIPLE","source_has_results":false},"controlled_terms":["Photoaging","Oral herbal supplement","Oral placebo supplement"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: skin aging.","quality_checked_at":"2026-09-25T06:20:17.523592+00:00","duplicate_cluster_key":"id:nct06146140","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2023-12-01 to 2024-12-01","comparator":"Oral Placebo Supplement","confidence":"structured-source","population":"FEMALE · 35 Years to 55 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:14.585Z","intervention":["Oral herbal supplement","Oral placebo supplement"],"participants":36,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · TRIPLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Change in Skin Elasticity — 8 weeks","Change in Skin Hydration — 8 weeks","Change in skin pigmentation intensity — 8 weeks","Change in appearance of facial wrinkles — 8 weeks","Change in the skin erythema — 8 weeks","Change in skin transepidermal water loss — 8 weeks","Self-perception of skin (changes in facial fine lines and wrinkles, firmness, etc) — 8 weeks","Product Tolerability — 8 weeks"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"skin-aging","is_published":true,"match_reasons":["Title contains controlled term: skin aging.","Abstract contains controlled term: photoaging.","Source terminology contains: photoaging.","Title supplies longevity context: aging.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Skin ageing","slug":"skin-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/39531","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}