{"type":"trials","record":{"id":39587,"source_id":"clinicaltrials-gov","external_id":"NCT04835259","title":"Efficacy of Topical Antioxidants in Tretment of Photoaging","brief_summary":"This randomized controlled trial study aims at investigating the efficacy and safety of topical antioxidants in treatment of a cohort of non-elderly volunteers with photoaged skin.","overall_status":"Unknown","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Sohag University","enrollment":90,"countries":[],"start_date":"2021-04-01","completion_date":"2022-06-01","last_update_date":"2021-04-20","source_url":"https://clinicaltrials.gov/study/NCT04835259","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:19.060264+00:00","last_seen_at":"2026-09-25T06:20:14.553+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"30 Years to 50 Years","comparator":"Group 1(treatment group); Group 2 (positive control); Group 3 (Negative control)","organization":"Sohag University","interventions":["Selenium Amino Acid Chelate (Selenium ACE cream)"],"registry_source":"ClinicalTrials.gov","outcome_measures":["change in Dermoscopy photoaging scale — assesed every month for 6 months"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","source_has_results":false},"controlled_terms":["Photoaging","Selenium Amino Acid Chelate (Selenium ACE cream)"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: photoaging.","quality_checked_at":"2026-09-25T06:20:17.523592+00:00","duplicate_cluster_key":"id:nct04835259","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2021-04-01 to 2022-06-01","comparator":"Group 1(treatment group); Group 2 (positive control); Group 3 (Negative control)","confidence":"structured-source","population":"ALL · 30 Years to 50 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:14.594Z","intervention":["Selenium Amino Acid Chelate (Selenium ACE cream)"],"participants":90,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["change in Dermoscopy photoaging scale — assesed every month for 6 months"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"skin-aging","is_published":true,"match_reasons":["Title contains controlled term: photoaging.","Source terminology contains: photoaging.","Title supplies longevity context: aging.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Skin ageing","slug":"skin-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/39587","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}