{"type":"trials","record":{"id":39632,"source_id":"clinicaltrials-gov","external_id":"NCT03425955","title":"Aesthetic Performance of an Intradermal Injection Treatment for Face Photoaging: Interstitial or Cushion Technique in Comparison to Bolus Technique at Five Points (Half - Face Method Within Subjects)","brief_summary":"Aesthetic performance of \"SUNEKOS® 200\" injectable treatment on main sign of face skin aging in normotypic or overweight subjects with rounded, oval or squared face and in thin subjects with oval or triangular face and \"sagging\" skin.Interstitial or cushion technique in comparison to bolus technique at five points (half - face method within subjects).","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Derming SRL","enrollment":12,"countries":["Italy"],"start_date":"2017-10-19","completion_date":"2017-12-21","last_update_date":"2018-02-08","source_url":"https://clinicaltrials.gov/study/NCT03425955","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:19.060264+00:00","last_seen_at":"2026-09-25T06:20:14.553+00:00","metadata":{"sex":"FEMALE","acronym":null,"age_range":"35 Years to 60 Years","comparator":null,"organization":"Derming SRL","interventions":["SUNEKOS ® 200","\"SUNEKOS® 1200\" and \"SUNEKOS® 200\""],"registry_source":"ClinicalTrials.gov","outcome_measures":["Variation of wrinkles grade of the area around the eyes — Baseline (T0), immediately after the 1st \"Sunekos® 200\" injec…","Variation of Wrinkle Severity Rating Scale (WSRS) grade — Baseline (T0), immediately after the 1st \"Sunekos® 200\" injec…","Variation of Facial Volume Loss Scale (FVLS) grade — Baseline (T0), immediately after the 1st \"Sunekos® 200\" injection…","Photographic documentation (3D pictures) — Baseline (T0), immediately after the 1st \"Sunekos® 200\" injection treatment…","Face volume variation — Baseline (T0), immediately after the 1st \"Sunekos® 200\" injection treatment (T1i), 60 days (T60…"],"design_description":"NON RANDOMIZED · PARALLEL · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Face Photoaging","SUNEKOS ® 200","\"SUNEKOS® 1200\" and \"SUNEKOS® 200\""],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: photoaging.","quality_checked_at":"2026-09-25T06:20:17.523592+00:00","duplicate_cluster_key":"id:nct03425955","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2017-10-19 to 2017-12-21","comparator":null,"confidence":"structured-source","population":"FEMALE · 35 Years to 60 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:14.600Z","intervention":["SUNEKOS ® 200","\"SUNEKOS® 1200\" and \"SUNEKOS® 200\""],"participants":12,"study_design":"NON RANDOMIZED · PARALLEL · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Variation of wrinkles grade of the area around the eyes — Baseline (T0), immediately after the 1st \"Sunekos® 200\" injec…","Variation of Wrinkle Severity Rating Scale (WSRS) grade — Baseline (T0), immediately after the 1st \"Sunekos® 200\" injec…","Variation of Facial Volume Loss Scale (FVLS) grade — Baseline (T0), immediately after the 1st \"Sunekos® 200\" injection…","Photographic documentation (3D pictures) — Baseline (T0), immediately after the 1st \"Sunekos® 200\" injection treatment…","Face volume variation — Baseline (T0), immediately after the 1st \"Sunekos® 200\" injection treatment (T1i), 60 days (T60…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"skin-aging","is_published":true,"match_reasons":["Title contains controlled term: photoaging.","Abstract contains controlled term: skin aging.","Source terminology contains: photoaging.","Title supplies longevity context: aging.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Skin ageing","slug":"skin-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/39632","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}