{"type":"trials","record":{"id":39637,"source_id":"clinicaltrials-gov","external_id":"NCT03274232","title":"Face Photoaging: Efficacy and Tolerance Evaluation of an Intradermal Injective Treatment","brief_summary":"Efficacy and tolerance evaluation of an intradermal injective treatment","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Derming SRL","enrollment":25,"countries":[],"start_date":"2016-10-27","completion_date":"2017-04-25","last_update_date":"2017-09-06","source_url":"https://clinicaltrials.gov/study/NCT03274232","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:19.060264+00:00","last_seen_at":"2026-09-25T06:20:14.553+00:00","metadata":{"sex":"FEMALE","acronym":null,"age_range":"45 Years to 65 Years","comparator":null,"organization":"Derming SRL","interventions":["SUNEKOS ® 200"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Variation of Wrinkle Severity Rating Scale (WSRS) grade — Basal visit (T0), 10 days(T2i), 20 days (T3i), 30 days (T4i),…","Variation of Facial Volume Loss Scale (FVLS) grade — Basal visit (T0), 10 days(T2i), 20 days (T3i), 30 days (T4i), 2 mo…","Superficial skin hydration variation — Basal visit (T0), 2 months (T2M) , 3 months (T3M), 6 months (T6M)","Deep skin hydration variation — Basal visit (T0), 2 months (T2M) , 3 months (T3M), 6 months (T6M)","Skin plastoelasticity variation — Basal visit (T0), 2 months (T2M) , 3 months (T3M), 6 months (T6M)","Variation of profilometric parameters — Basal visit (T0), 2 months (T2M) , 3 months (T3M), 6 months (T6M)","Photographic documentation (3D pictures ) — Basal visit (T0), 2 months (T2M) , 3 months (T3M), 6 months (T6M)","Face volume variation — Basal visit (T0), 2 months (T2M) , 3 months (T3M), 6 months (T6M)"],"design_description":"NA · SINGLE GROUP · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Face Skin Photoaging","SUNEKOS ® 200"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: photoaging.","quality_checked_at":"2026-09-25T06:20:17.523592+00:00","duplicate_cluster_key":"id:nct03274232","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2016-10-27 to 2017-04-25","comparator":null,"confidence":"structured-source","population":"FEMALE · 45 Years to 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:14.601Z","intervention":["SUNEKOS ® 200"],"participants":25,"study_design":"NA · SINGLE GROUP · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Variation of Wrinkle Severity Rating Scale (WSRS) grade — Basal visit (T0), 10 days(T2i), 20 days (T3i), 30 days (T4i),…","Variation of Facial Volume Loss Scale (FVLS) grade — Basal visit (T0), 10 days(T2i), 20 days (T3i), 30 days (T4i), 2 mo…","Superficial skin hydration variation — Basal visit (T0), 2 months (T2M) , 3 months (T3M), 6 months (T6M)","Deep skin hydration variation — Basal visit (T0), 2 months (T2M) , 3 months (T3M), 6 months (T6M)","Skin plastoelasticity variation — Basal visit (T0), 2 months (T2M) , 3 months (T3M), 6 months (T6M)","Variation of profilometric parameters — Basal visit (T0), 2 months (T2M) , 3 months (T3M), 6 months (T6M)","Photographic documentation (3D pictures ) — Basal visit (T0), 2 months (T2M) , 3 months (T3M), 6 months (T6M)","Face volume variation — Basal visit (T0), 2 months (T2M) , 3 months (T3M), 6 months (T6M)"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"skin-aging","is_published":true,"match_reasons":["Title contains controlled term: photoaging.","Source terminology contains: photoaging.","Title supplies longevity context: aging.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Skin ageing","slug":"skin-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/39637","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}