{"type":"trials","record":{"id":39641,"source_id":"clinicaltrials-gov","external_id":"NCT00248989","title":"Effect of DHEA on Skin Aging in Postmenopausal Women","brief_summary":"The purpose of the study is to determine the response of skin parameters related to skin aging to the local action of DHEA in postmenopausal women.","overall_status":"Completed","phases":["PHASE3"],"study_type":"INTERVENTIONAL","sponsor":"CHU de Quebec-Universite Laval","enrollment":150,"countries":["Canada"],"start_date":"2004-11-01","completion_date":"2008-11-13","last_update_date":"2017-04-07","source_url":"https://clinicaltrials.gov/study/NCT00248989","editorial_summary":"A registered PHASE3 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:19.060264+00:00","last_seen_at":"2026-09-25T06:20:14.553+00:00","metadata":{"sex":"FEMALE","acronym":null,"age_range":"60 Years to 65 Years","comparator":null,"organization":"CHU de Quebec-Universite Laval","interventions":["Dehydroepiandrosterone","Placebos"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Determination of local activity of DHEA for a 12 months period in parameters such as wrinkles, sebaceous gland activity…","Evaluation of tolerance to local skin application of DHEA for a 12 months period and potential beneficial effects on qu…"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · QUADRUPLE","source_has_results":false},"controlled_terms":["Skin Aging","Quality of Life","Dehydroepiandrosterone","Placebos"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: skin aging.","quality_checked_at":"2026-09-25T06:20:17.523592+00:00","duplicate_cluster_key":"id:nct00248989","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2004-11-01 to 2008-11-13","comparator":null,"confidence":"structured-source","population":"FEMALE · 60 Years to 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:14.602Z","intervention":["Dehydroepiandrosterone","Placebos"],"participants":150,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · QUADRUPLE","subject_scope":"Human clinical study registration","evidence_stage":"PHASE3","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Determination of local activity of DHEA for a 12 months period in parameters such as wrinkles, sebaceous gland activity…","Evaluation of tolerance to local skin application of DHEA for a 12 months period and potential beneficial effects on qu…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"skin-aging","is_published":true,"match_reasons":["Title contains controlled term: skin aging.","Abstract contains controlled term: skin aging.","Source terminology contains: skin aging.","Title supplies longevity context: aging.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Skin ageing","slug":"skin-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/39641","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}