{"type":"trials","record":{"id":39667,"source_id":"clinicaltrials-gov","external_id":"NCT01898182","title":"Efficacy and Safety of Kinetin 0.1% for Treatment of Skin Photoaging","brief_summary":"The purpose of the study is to evaluate the change in the severity and clinical signs of skin photoaging among Filipino patients using Kinerase cream (Kinetin 0.1%). This study will recruit 132 subjects from dermatological clinics in a tertiary hospital in the Philippines for a period of 3 months (12 weeks). Changes in severity will be documented using physician evaluation, self-evaluation, and through VISIA complexion analysis system.","overall_status":"Completed","phases":["PHASE4"],"study_type":"INTERVENTIONAL","sponsor":"Makati Medical Center","enrollment":132,"countries":["Philippines"],"start_date":"2013-11-01","completion_date":"2014-09-01","last_update_date":"2014-09-15","source_url":"https://clinicaltrials.gov/study/NCT01898182","editorial_summary":"A registered PHASE4 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:19.060264+00:00","last_seen_at":"2026-09-25T06:20:14.553+00:00","metadata":{"sex":"FEMALE","acronym":null,"age_range":"35 Years to 65 Years","comparator":null,"organization":"Makati Medical Center","interventions":["Kinetin, N6-furfuryladenine, 0.1%"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Skin Roughness — 12 weeks","Pigmentation — 12 weeks","Fine wrinkles — 12 weeks","Global Improvement in Cutaneous Photoaging — 12 weeks","Pores — 12 weeks","Wrinkles — 12 weeks","Texture — 12 weeks","Porphyrins — 12 weeks","Visual Spots — 12 weeks","UV spots — 12 weeks","Brown Spots — 12 weeks","Red Areas — 12 weeks","Erythema — 12 weeks","Burning — 12 weeks","Peeling — 12 weeks","Pruritus — 12 weeks","Dryness — 12 weeks","Edema — 12 weeks","Acne — 12 weeks"],"design_description":"NA · SINGLE GROUP · NONE","source_has_results":false},"controlled_terms":["Cutaneous Photoaging","Kinetin, N6-furfuryladenine, 0.1%"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":35,"publication_state":"published","match_explanation":"Title contains controlled term: photoaging.","quality_checked_at":"2026-09-25T06:20:17.523592+00:00","duplicate_cluster_key":"id:nct01898182","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2013-11-01 to 2014-09-01","comparator":null,"confidence":"structured-source","population":"FEMALE · 35 Years to 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:14.605Z","intervention":["Kinetin, N6-furfuryladenine, 0.1%"],"participants":132,"study_design":"NA · SINGLE GROUP · NONE","subject_scope":"Human clinical study registration","evidence_stage":"PHASE4","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Skin Roughness — 12 weeks","Pigmentation — 12 weeks","Fine wrinkles — 12 weeks","Global Improvement in Cutaneous Photoaging — 12 weeks","Pores — 12 weeks","Wrinkles — 12 weeks","Texture — 12 weeks","Porphyrins — 12 weeks","Visual Spots — 12 weeks","UV spots — 12 weeks","Brown Spots — 12 weeks","Red Areas — 12 weeks","Erythema — 12 weeks","Burning — 12 weeks","Peeling — 12 weeks","Pruritus — 12 weeks","Dryness — 12 weeks","Edema — 12 weeks","Acne — 12 weeks"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"skin-aging","is_published":true,"match_reasons":["Title contains controlled term: photoaging.","Abstract contains controlled term: photoaging.","Source terminology contains: photoaging.","Title supplies longevity context: aging.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Skin ageing","slug":"skin-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/39667","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}