{"type":"trials","record":{"id":40233,"source_id":"clinicaltrials-gov","external_id":"NCT02214485","title":"Integrated Care and Lower Extremity Strength Training Among Community-Dwelling Frail Older Adults in Taiwan","brief_summary":"Objective: To determine the differential effectiveness of integrated care (IC) and lower extremity strength training (LEST) among community-dwelling frail older adults in Taiwan. Method: The investigators randomize participants at Bei-Hu site from the \"Intervention study of Geriatric Frailty, Osteoporosis, and Depression in a Community Based Randomized Trial\" into 12 weeks of either IC or LEST. Outcome assessments are performed at baseline, 12 weeks and 6 months after initiation of the interventions. Interventions: 1. IC: Participants visit the study site with health education, social activities, warm up, stretch, and low intensity resistance exercise for about 1 hour per week. If any medical problems or functional decline suspected during the visit, the case manager refers participants to their primary care physicians for further managements. 2. LEST: Participants receive 2 sessions of 30-minute lower extremity strength straining using isotonic strength training machines each week. The intensity is set at 60-80% of 1 repetition maximum (RM). Evaluation of the exercise protocol are repeated every 2 weeks for individualized adjustments","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"National Taiwan University Hospital","enrollment":98,"countries":["Taiwan"],"start_date":"2011-03-01","completion_date":"2012-02-01","last_update_date":"2014-08-12","source_url":"https://clinicaltrials.gov/study/NCT02214485","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:22.160691+00:00","last_seen_at":"2026-09-25T06:20:19.667+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years to 79 Years","comparator":null,"organization":"National Taiwan University Hospital","interventions":["integrated care","lower extremity strength training"],"registry_source":"ClinicalTrials.gov","outcome_measures":["leg extension power — changes in 12 weeks"],"design_description":"RANDOMIZED · SINGLE GROUP · SINGLE","source_has_results":false},"controlled_terms":["Frailty","integrated care","lower extremity strength training"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":35,"publication_state":"published","match_explanation":"Title contains controlled term: strength training.","quality_checked_at":"2026-09-25T06:20:27.00315+00:00","duplicate_cluster_key":"id:nct02214485","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2011-03-01 to 2012-02-01","comparator":null,"confidence":"structured-source","population":"ALL · 65 Years to 79 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:19.772Z","intervention":["integrated care","lower extremity strength training"],"participants":98,"study_design":"RANDOMIZED · SINGLE GROUP · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["leg extension power — changes in 12 weeks"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"resistance-training","is_published":true,"match_reasons":["Title contains controlled term: strength training.","Abstract contains controlled term: strength training.","Source terminology contains: strength training.","Title supplies longevity context: frail, older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Resistance training","slug":"resistance-training"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/40233","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}