{"type":"trials","record":{"id":41091,"source_id":"clinicaltrials-gov","external_id":"NCT03117231","title":"Effects of tDCS in Elderly With Pain Due to Knee Osteoarthritis","brief_summary":"The purpose of this study is to evaluate if anodal tDCS stimulation over M1 may decrease chronic knee OA pain in elderly subjects with defective CPM. In addition, this trial will help to investigate the role of central sensitization in knee OA and evaluate how tDCS stimulation may affect it.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Federal University of São Paulo","enrollment":104,"countries":["Brazil"],"start_date":"2018-03-15","completion_date":"2019-07-01","last_update_date":"2019-09-09","source_url":"https://clinicaltrials.gov/study/NCT03117231","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:26.536053+00:00","last_seen_at":"2026-09-25T03:10:58.794+00:00","metadata":{"acronym":null,"organization":"Federal University of São Paulo","source_has_results":false},"controlled_terms":["Osteoarthritis, Knee","Chronic Pain","Active Transcranial Direct Current Stimulation (tDCS)","Sham Transcranial Direct Current Stimulation (tDCS)"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: osteoarthritis.","quality_checked_at":"2026-09-25T03:11:01.385369+00:00","duplicate_cluster_key":"id:nct03117231","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2018-03-15 to 2019-07-01","comparator":null,"confidence":"structured-source","population":null,"provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:40:00.377838+00:00","intervention":[],"participants":104,"study_design":"INTERVENTIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":[],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"joint-cartilage-aging","is_published":true,"match_reasons":["Title contains controlled term: osteoarthritis.","Source terminology contains: osteoarthritis.","Title supplies longevity context: elderly.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Joint and cartilage ageing","slug":"joint-cartilage-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/41091","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}