{"type":"trials","record":{"id":41194,"source_id":"clinicaltrials-gov","external_id":"NCT01328340","title":"High-speed Power Training in Older Adults With Knee Osteoarthritis (OA)","brief_summary":"We are exploring a unique weight-training program for men and women 55 years or older with knee osteoarthritis (OA) that emphasizes high-speed movements. We believe that the speed at which muscles move may be more important to the improvement of muscle performance, function and pain than how strong the muscles are. We are comparing high-speed power training with traditional strength training to determine which method has the greatest effects on muscle strength, muscle power, speed of movement, functional performance and pain. We believe that high-speed training will improve these measures to a greater extent than simply training for increased muscle strength.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"University of Missouri-Columbia","enrollment":48,"countries":["United States"],"start_date":"2005-06-01","completion_date":"2008-05-01","last_update_date":"2016-10-04","source_url":"https://clinicaltrials.gov/study/NCT01328340","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:26.536053+00:00","last_seen_at":"2026-09-25T05:35:07.553+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"55 Years","comparator":"High-speed power training; Slow-speed strength training; Control","organization":"University of Missouri-Columbia","interventions":["High-speed power training","Slow-speed strength training"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Strength and power — 3 months","Function — 3 months"],"design_description":"RANDOMIZED · FACTORIAL · TREATMENT · TRIPLE","source_has_results":false},"controlled_terms":["Knee Osteoarthritis","High-speed power training","Slow-speed strength training"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: osteoarthritis.","quality_checked_at":"2026-09-25T05:35:12.977559+00:00","duplicate_cluster_key":"id:nct01328340","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2005-06-01 to 2008-05-01","comparator":"High-speed power training; Slow-speed strength training; Control","confidence":"structured-source","population":"ALL · 55 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T05:35:07.576Z","intervention":["High-speed power training","Slow-speed strength training"],"participants":48,"study_design":"RANDOMIZED · FACTORIAL · TREATMENT · TRIPLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Strength and power — 3 months","Function — 3 months"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"joint-cartilage-aging","is_published":true,"match_reasons":["Title contains controlled term: osteoarthritis.","Abstract contains controlled term: osteoarthritis.","Source terminology contains: osteoarthritis.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Joint and cartilage ageing","slug":"joint-cartilage-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/41194","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}