{"type":"trials","record":{"id":41375,"source_id":"clinicaltrials-gov","external_id":"NCT07144137","title":"A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)","brief_summary":"This is a non-interventional, observational study to provide insights into the short-term progression of GA secondary to AMD in participants aged ≥55 years. This is a multi-center, non-interventional, observational study which aims to identify participants who have progressive GA to allow quantification of structural and functional parameters that characterize the progression of GA, and to investigate whether these correlate with genetic or lifestyle factors.","overall_status":"Recruiting","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Complement Therapeutics","enrollment":75,"countries":["United States","United Kingdom"],"start_date":"2025-07-30","completion_date":"2027-06-30","last_update_date":"2026-09-03","source_url":"https://clinicaltrials.gov/study/NCT07144137","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":"Pre-GAIN","age_range":"55 Years","comparator":null,"organization":"Complement Therapeutics","interventions":[],"registry_source":"ClinicalTrials.gov","outcome_measures":["Short-term GA Progression — Baseline, Month 3, Month 6","Further exploration of GA progression — Baseline, Month 3, Month 6"],"design_description":null,"source_has_results":false},"controlled_terms":["Geographic Atrophy Secondary to Age-related Macular Degeneration"],"relevance_confidence":60,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Source terminology contains: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct07144137","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-07-30 to 2027-06-30","comparator":null,"confidence":"structured-source","population":"ALL · 55 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.801Z","intervention":[],"participants":75,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Short-term GA Progression — Baseline, Month 3, Month 6","Further exploration of GA progression — Baseline, Month 3, Month 6"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Source terminology contains: age-related macular degeneration.","Source terminology supplies longevity context: age-related.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["controlled terminology","controlled context","study type"],"relevance_score":60,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/41375","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}