{"type":"trials","record":{"id":41377,"source_id":"clinicaltrials-gov","external_id":"NCT07798323","title":"Noninvasive Imaging Biomarkers of Treatable Macrovascular Disease in Age-related Macular Degeneration.","brief_summary":"The purpose of this prospective study is to investigate whether ophthalmic artery stenosis (narrowing of the ophthalmic artery) contributes to the development and progression of geographic atrophy (GA), an advanced form of dry age-related macular degeneration (AMD).","overall_status":"Recruiting","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Scott Raymond","enrollment":30,"countries":["United States"],"start_date":"2026-09-01","completion_date":"2028-12-01","last_update_date":"2026-09-03","source_url":"https://clinicaltrials.gov/study/NCT07798323","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:25:30.378222+00:00","last_seen_at":"2026-09-25T06:20:47.789+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"50 Years to 80 Years","comparator":null,"organization":"The Cleveland Clinic","interventions":[],"registry_source":"ClinicalTrials.gov","outcome_measures":["To demonstrate the ability to quantify ophthalmic artery stenosis using a commercially available, non-invasive imaging…","To provide compelling evidence for a connection between ophthalmic artery stenosis and OCT markers of dry AMD disease s…"],"design_description":null,"source_has_results":false},"controlled_terms":["Macular Degeneration"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: age-related macular degeneration.","quality_checked_at":"2026-09-25T06:20:59.355028+00:00","duplicate_cluster_key":"id:nct07798323","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2026-09-01 to 2028-12-01","comparator":null,"confidence":"structured-source","population":"ALL · 50 Years to 80 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:47.801Z","intervention":[],"participants":30,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["To demonstrate the ability to quantify ophthalmic artery stenosis using a commercially available, non-invasive imaging…","To provide compelling evidence for a connection between ophthalmic artery stenosis and OCT markers of dry AMD disease s…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"vision-aging","is_published":true,"match_reasons":["Title contains controlled term: age-related macular degeneration.","Abstract contains controlled term: age-related macular degeneration.","Title supplies longevity context: aging, age-related.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Vision ageing","slug":"vision-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/41377","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}